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  • Drotrecogin alpha
  • Sepsis
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    12003Role of activated protein C in the pathophysiology of severe sepsis.



    +-nlAm J Crit Care 12(6):518-24; quiz 525-6 (2003)
    22008Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated).



    +-nlCrit Care 12(2):R45 (2008)
    32007Practical aspects of treatment with drotrecogin alfa (activated).



    +-nlCrit Care 11 Suppl 5(-):S7 (2007)
    42007The safety profile of drotrecogin alfa (activated).



    +-nlCrit Care 11 Suppl 5(-):S6 (2007)
    52007Clinical trials in severe sepsis with drotrecogin alfa (activated).



    +-nlCrit Care 11 Suppl 5(-):S5 (2007)
    62007The protein C pathway: implications for the design of the RESPOND study.



    +-nlCrit Care 11 Suppl 5(-):S4 (2007)
    72007Recombinant human activated protein C: current insights into its mechanism of action.



    +-nlCrit Care 11 Suppl 5(-):S3 (2007)
    82007Recombinant activated protein C in sepsis: endothelium protection or endothelium therapy?



    +-nlCrit Care 11(1):103 (2007)
    92003Clinical review: Drotrecogin alfa (activated) as adjunctive therapy for severe sepsis--practical aspects at the bedside and patient identification.



    +-nlCrit Care 7(6):445-50 (2003)
    102007Drotrecogin alfa (activated) in severe sepsis: a systematic review and new cost-effectiveness analysis.



    +-nlBMC Anesthesiol 7(-):5 (2007)
    112006Treatment of severe sepsis: where next? Current and future treatment approaches after the introduction of drotrecogin alfa.



    +-nlVasc Health Risk Manag 2(1):3-18 (2006)
    122009Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies.



    +-nlBiologics 3(-):391-406 (2009)
    132005Clinical effectiveness and cost-effectiveness of drotrecogin alfa (activated) (Xigris) for the treatment of severe sepsis in adults: a systematic review and economic evaluation.



    +-nlHealth Technol Assess 9(11):1-126, iii-iv (2005)
    142009Modulation of sepsis outcome with variants of activated protein C.



    +-nlJ Thromb Haemost 7 Suppl 1(-):127-31 (2009)
    152007Activated protein C.



    +-nlJ Thromb Haemost 5 Suppl 1(-):73-80 (2007)
    162004Activated protein C in sepsis.



    +-nlJ Thromb Haemost 2(5):708-17 (2004)
    172003Drotrecogin alfa (activated): a novel therapeutic strategy for severe sepsis.



    +-nlPostgrad Med J 79(927):5-10 (2003)
    182009Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study.



    +-nlAm J Respir Crit Care Med 180(9):861-6 (2009)
    192007Activated protein C: cost-effective or costly?



    +-nlCrit Care 11(5):164 (2007) Brar SS
    202009Treatment of septic shock and use of drotrecogin alfa (activated) in children.



    +-nlExpert Rev Anti Infect Ther 7(7):769-72 (2009)



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