| Nr. | Year OPEN | Title | users say> | rate good | rate bad | no link | Citation |
Crohn s diseaseAdalimumabNatalizumabMycobacterium avium paratuberculosisNod2Colon and rectum (Stent)Certolizumab pegolFistula (Intestine)DefensinDysbiosisArthritis (rheumatoid)Bartonella henselaeCandida (BASKET)CoccidioidomycosisOvary (Neoplasia)Gastrointestinal stromal cell tumor GISTHistoplasmosisTestis (Neoplasia)Lymphoma (Hodgkin)Calcium (Hypercalciemia)CryptococcosisLangerhans cell histiocytosisLiver (Diseases)LepraLung (Neoplasm)Lymphoma (BASKET)OsteoarthritisSarcoidosisTuberculosisWegener s granulomatosisPneumocystis carinii Pneumocystis jiroviciiParacoccoidomycosisBacillus calmette guerinPseudolymphoma (Lymphomatoid granulomatosis)Lipoid pneumoniaLung (Toxicology)PolymyositisSiliconeSlack skin diseaseFat necrosis subcutaneous of the newbornPseudolymphoma (Plasma cell granuloma)Testis (Neoplasia Seminoma)Antibodies (Anti Saccharomyces cerevisiae)| 1 | 1999 | Management of Crohn's disease. | 
| + | - | nl | BMJ 319(7223):1480-5 (1999) |
| 2 | 1997 | Neurologic and neuropsychiatric complications of Crohn's disease. | 
| + | - | nl | South Med J 90(6):606-10 (1997) |
| 3 | 2006 | Guidelines for treatment with infliximab for Crohn's disease. | 
| + | - | nl | Neth J Med 64(7):219-29 (2006) Hommes DW |
| 4 | 2006 | Infliximab use in patients with Crohn's disease: quality of life, costs and resource use. | 
| + | - | nl | Neth J Med 64(7):212-8 (2006) Koelewijn C |
| 5 | 2006 | The Dutch guidelines for treatment with infliximab for Crohn's disease. | 
| + | - | nl | Neth J Med 64(7):210-1 (2006) |
| 6 | 2008 | Adalimumab for the treatment of Crohn's disease. | 
| + | - | nl | Biologics 2(4):763-77 (2008) |
| 7 | 2008 | Natalizumab in the treatment of Crohn's disease. | 
| + | - | nl | Biologics 2(2):275-84 (2008) |
| 8 | 2009 | An evidence-based review of natalizumab therapy in the management of Crohn's disease. | 
| + | - | nl | Ther Clin Risk Manag 5(-):935-42 (2009) |
| 9 | 2009 | Where are all the Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease? | 
| + | - | nl | PLoS Pathog 5(3):e1000234 (2009) |
| 10 | 2002 | Crohn's disease caused by Mycobacterium avium subspecies paratuberculosis: a public health tragedy whose resolution is long overdue. | 
| + | - | nl | J Med Microbiol 51(1):3-6 (2002) |
| 11 | 1994 | The role of mycobacteria in Crohn's disease. | 
| + | - | nl | J Med Microbiol 41(2):74-94 (1994) |
| 12 | 2004 | Disappearance of Crohn's ulcers in the terminal ileum after thalidomide therapy. | 
| + | - | nl | Can J Gastroenterol 18(2):101-4 (2004) |
| 13 | 2005 | Surgery for small bowel Crohn's disease: experience of a tertiary referral center. | 
| + | - | nl | Saudi J Gastroenterol 11(2):85-92 (2005) |
| 14 | 2005 | Neutrophil expression and infiltration into Crohn's intestine. | 
| + | - | nl | Saudi J Gastroenterol 11(2):63-72 (2005) |
| 15 | 2009 | Role of flagellin in Crohn's disease: emblematic of the progress and enigmas in understanding inflammatory bowel disease. | 
| + | - | nl | Inflamm Bowel Dis 15(5):789-95 (2009) |
| 16 | 2009 | Postoperative therapy for Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 15(3):463-72 (2009) |
| 17 | 2009 | Intestinal dendritic cells and epithelial barrier dysfunction in Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 15(3):436-53 (2009) |
| 18 | 2009 | Positioning biologic agents in the treatment of Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 15(10):1570-82 (2009) |
| 19 | 2005 | A review of activity indices and end points for clinical trials in children with Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 11(2):185-96 (2005) |
| 20 | 2004 | Clinical characteristics of familial versus sporadic Crohn's disease using the Vienna Classification. | 
| + | - | nl | Inflamm Bowel Dis 10(3):201-6 (2004) |
| 21 | 2004 | 6-Mercaptopurine is effective in Crohn's disease without concomitant steroids. | 
| + | - | nl | Inflamm Bowel Dis 10(2):79-84 (2004) |
| 22 | 2004 | Medical therapy for Crohn's disease strictures. | 
| + | - | nl | Inflamm Bowel Dis 10(1):55-60 (2004) |
| 23 | 2002 | Management of internal fistulas in Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 8(2):106-11 (2002) |
| 24 | 2001 | Approach to corticosteroid-dependent and corticosteroid-refractory Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 7 Suppl 1(-):S23-9 (2001) |
| 25 | 2001 | Measles virus and Crohn's disease: a critical appraisal of the current literature. | 
| + | - | nl | Inflamm Bowel Dis 7(1):51-7 (2001) |
| 26 | 2000 | Prevention of relapse of Crohn's disease. | 
| + | - | nl | Inflamm Bowel Dis 6(4):321-8; discussion 329 (2000) |
| 27 | 2000 | A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. | 
| + | - | nl | Inflamm Bowel Dis 6(1):8-15 (2000) |
| 28 | 1998 | Immunotherapy of Crohn's disease. | 
| + | - | nl | Mediators Inflamm 7(3):149-52 (1998) |
| 29 | 2005 | NOD2 and Crohn's disease: loss or gain of function? | 
| + | - | nl | Immunity 22(6):661-7 (2005) |
| 30 | 2001 | Autoimmunity and apoptosis: the Crohn's connection. | 
| + | - | nl | Immunity 15(1):5-14 (2001) |
| 31 | 1998 | The many faces of malnutrition in Crohn disease. | 
| + | - | nl | Am J Clin Nutr 67(5):819-20 (1998) |
| 32 | 1990 | Anal lesions in Crohn's disease. | 
| + | - | nl | Ann R Coll Surg Engl 72(3):158-9 (1990) |
| 33 | 1990 | Pathology of Crohn's disease. | 
| + | - | nl | Ann R Coll Surg Engl 72(3):150-1 (1990) |
| 34 | 1993 | Incidence, diagnosis, and treatment of enteric and colorectal fistulae in patients with Crohn's disease. | 
| + | - | nl | Ann Surg 218(5):660-6 (1993) |
| 35 | 1987 | Spontaneous free perforation and perforated abscess in 30 patients with Crohn's disease. | 
| + | - | nl | Ann Surg 205(1):72-6 (1987) |
| 36 | 1982 | The long-term outcome of restorative operation in Crohn's disease: influence of location, prognostic factors and surgical guidelines. | 
| + | - | nl | Ann Surg 196(3):345-55 (1982) |
| 37 | 1978 | Comparison of the results of resection, bypass, and bypass with exclusion for ileocecal Crohn's disease. | 
| + | - | nl | Ann Surg 187(5):530-5 (1978) |
| 38 | 2008 | Systematic review: nutritional therapy in paediatric Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 27(4):293-307 (2008) |
| 39 | 2008 | Review article: the evidence base for interventions used to maintain remission in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 27(1):11-8 (2008) |
| 40 | 2007 | Systematic review: Endoscopic dilatation in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 26(11-12):1457-64 (2007) |
| 41 | 2007 | Medical management of mild to moderate Crohn's disease: evidence-based treatment algorithms for induction and maintenance of remission. | 
| + | - | nl | Aliment Pharmacol Ther 26(7):987-1003 (2007) |
| 42 | 2007 | Meta-analysis: enteral nutrition in active Crohn's disease in children. | 
| + | - | nl | Aliment Pharmacol Ther 26(6):795-806 (2007) |
| 43 | 2007 | Review article: appropriate use of corticosteroids in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 26(3):313-29 (2007) |
| 44 | 2007 | Systematic review: the potential influence of mesalazine formulation on maintenance of remission in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 25(12):1389-99 (2007) |
| 45 | 2007 | Review article: the diagnosis and management of Crohn's disease in populations with high-risk rates for tuberculosis. | 
| + | - | nl | Aliment Pharmacol Ther 25(12):1373-88 (2007) |
| 46 | 2007 | Meta-analysis: mortality in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 25(8):861-70 (2007) |
| 47 | 2007 | Review article: Altering the natural history of Crohn's disease--evidence for and against current therapies. | 
| + | - | nl | Aliment Pharmacol Ther 25(1):3-12 (2007) |
| 48 | 2006 | Systematic review: managing anaemia in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 24(11-12):1507-23 (2006) |
| 49 | 2006 | Review article: Medical therapy for fistulizing Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 24(9):1283-93 (2006) |
| 50 | 2006 | Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 23(8):1097-104 (2006) |
| 51 | 2005 | Polypharmacy and Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 21(10):1211-6 (2005) |
| 52 | 2005 | Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 21(6):733-8 (2005) |
| 53 | 2004 | Systematic review: has disease outcome in Crohn's disease changed during the last four decades? | 
| + | - | nl | Aliment Pharmacol Ther 20(5):483-96 (2004) |
| 54 | 2004 | How effective are the usual treatments for Crohn's disease? | 
| + | - | nl | Aliment Pharmacol Ther 20(2):151-9 (2004) |
| 55 | 2004 | Review article: The medical treatment of Crohn's perianal fistulas. | 
| + | - | nl | Aliment Pharmacol Ther 19(9):953-67 (2004) |
| 56 | 2003 | Fistula response to methotrexate in Crohn's disease: a case series. | 
| + | - | nl | Aliment Pharmacol Ther 18(10):1003-8 (2003) |
| 57 | 2003 | Review article: mild to moderate Crohn's disease--defining the basis for a new treatment algorithm. | 
| + | - | nl | Aliment Pharmacol Ther 18(3):263-77 (2003) |
| 58 | 2002 | Review article: biological agents in the treatment of Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 16(9):1579-90 (2002) |
| 59 | 2002 | The effectiveness of budesonide therapy for Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 16(8):1509-17 (2002) |
| 60 | 2002 | Review article: is clinical remission the optimum therapeutic goal in the treatment of Crohn's disease? | 
| + | - | nl | Aliment Pharmacol Ther 16(5):857-67 (2002) |
| 61 | 2002 | The epidemiology and natural history of Crohn's disease in population-based patient cohorts from North America: a systematic review. | 
| + | - | nl | Aliment Pharmacol Ther 16(1):51-60 (2002) |
| 62 | 2001 | Review article: the immunoregulatory cytokine interleukin-10--a therapy for Crohn's disease? | 
| + | - | nl | Aliment Pharmacol Ther 15(11):1709-16 (2001) |
| 63 | 2001 | Review article: the limitations of corticosteroid therapy in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 15(10):1515-25 (2001) |
| 64 | 2001 | Review article: the management of severe Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 15(5):563-73 (2001) |
| 65 | 2000 | Budesonide in the treatment of Crohn's disease: a meta-analysis. | 
| + | - | nl | Aliment Pharmacol Ther 14(11):1419-28 (2000) |
| 66 | 2010 | Review article: anti-fibrotic agents for the treatment of Crohn's disease - lessons learnt from other diseases. | 
| + | - | nl | Aliment Pharmacol Ther 31(2):189-201 (2010) |
| 67 | 2009 | Meta-analysis: the efficacy and safety of certolizumab pegol in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 29(6):605-14 (2009) |
| 68 | 2008 | Meta-analysis: remission and response from control arms of randomized trials of biological therapies for active luminal Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 27(12):1210-23 (2008) |
| 69 | 2004 | Review article: treatment of perianal fistulizing Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 20 Suppl 4(-):106-10 (2004) |
| 70 | 2002 | Review article: indication and type of surgery in Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 16 Suppl 4(-):59-64 (2002) |
| 71 | 2002 | Review article: Crohn's disease--the role of nutritional therapy. | 
| + | - | nl | Aliment Pharmacol Ther 16 Suppl 4(-):48-52 (2002) |
| 72 | 2002 | Review article: the management of refractory Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 16 Suppl 4(-):40-7 (2002) |
| 73 | 2002 | Review article: medical treatment of active Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 16 Suppl 4(-):35-9 (2002) |
| 74 | 2002 | Review article: monitoring the activity of Crohn's disease. | 
| + | - | nl | Aliment Pharmacol Ther 16 Suppl 4(-):29-33 (2002) |
| 75 | 2001 | Diagnosis and treatment of perianal fistulas in Crohn disease. | 
| + | - | nl | Ann Intern Med 135(10):906-18 (2001) |
| 76 | 2006 | European evidence based consensus on the diagnosis and management of Crohn's disease: special situations. | 
| + | - | nl | Gut 55 Suppl 1(-):i36-58 (2006) |
| 77 | 2006 | European evidence based consensus on the diagnosis and management of Crohn's disease: current management. | 
| + | - | nl | Gut 55 Suppl 1(-):i16-35 (2006) |
| 78 | 2006 | European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. | 
| + | - | nl | Gut 55 Suppl 1(-):i1-15 (2006) |
| 79 | 2005 | Mucosal integrity and barrier function in the pathogenesis of early lesions in Crohn's disease. | 
| + | - | nl | J Clin Pathol 58(6):568-72 (2005) |
| 80 | 1949 | Crohn's disease; a review. | 
| + | - | nl | Postgrad Med J 25(284):245-54 (1949) |
| 81 | 2004 | Cross-sectional imaging in Crohn disease. | 
| + | - | nl | Radiographics 24(3):689-702 (2004) |
| 82 | 1996 | Manifestations of Crohn disease at US. | 
| + | - | nl | Radiographics 16(3):499-520; discussion 520-1 (1996) |
| 83 | 1988 | Crohn's disease: less common radiographic manifestations. | 
| + | - | nl | Radiographics 8(2):259-75 (1988) |
| 84 | 2010 | MR enterographic manifestations of small bowel Crohn disease. | 
| + | - | nl | Radiographics 30(2):367-84 (2010) |
| 85 | 2006 | Crohn disease of the small bowel: preliminary comparison among CT enterography, capsule endoscopy, small-bowel follow-through, and ileoscopy. | 
| + | - | nl | Radiology 238(1):128-34 (2006) |
| 86 | 2005 | Role of US in detection of Crohn disease: meta-analysis. | 
| + | - | nl | Radiology 236(1):95-101 (2005) |
| 87 | 1997 | Crohn disease: state of the art. | 
| + | - | nl | Radiology 202(3):597-610 (1997) |
| 88 | 2004 | Inflammatory bowel disease. Part II: Crohn's disease--pathophysiology and conventional and alternative treatment options. | 
| + | - | nl | Altern Med Rev 9(4):360-401 (2004) |
| 89 | 2007 | TLRs in the Gut. III. Immune responses to flagellin in Crohn's disease: good, bad, or irrelevant? | 
| + | - | nl | Am J Physiol Gastrointest Liver Physiol 292(3):G706-10 (2007) |
| 90 | 2008 | Magnetic resonance imaging in Crohn's disease. | 
| + | - | nl | BMJ 336(7638):273-6 (2008) |
| 91 | 2011 | Crohn's disease: evidence for involvement of unregulated transcytosis in disease etio-pathogenesis. | 
| + | - | nl | World J Gastroenterol 17(11):1416-26 (2011) |
| 92 | 2011 | Current treatment of rectovaginal fistula in Crohn's disease. | 
| + | - | nl | World J Gastroenterol 17(8):963-7 (2011) |
| 93 | 2011 | Defensins couple dysbiosis to primary immunodeficiency in Crohn's disease. | 
| + | - | nl | World J Gastroenterol 17(5):567-71 (2011) |
| 94 | 2011 | Role of conventional therapies in the era of biological treatment in Crohn's disease. | 
| + | - | nl | World J Gastroenterol 17(14):1797-806 (2011) |
| 95 | 2011 | Perianal Crohn's disease: is there something new? | 
| + | - | nl | World J Gastroenterol 17(15):1939-46 (2011) |
| 96 | 2010 | Efficacy of early treatment with infliximab in pediatric Crohn's disease. | 
| + | - | nl | World J Gastroenterol 16(14):1776-81 (2010) |
| 97 | 2008 | Crohn's disease--defect in innate defence. | 
| + | - | nl | World J Gastroenterol 14(36):5499-503 (2008) |
| 98 | 2010 | Long-term antibiotic treatment for Crohn's disease: systematic review and meta-analysis of placebo-controlled trials. | 
| + | - | nl | Clin Infect Dis 50(4):473-80 (2010) |
| 99 | 2007 | The role of microbes in Crohn's disease. | 
| + | - | nl | Clin Infect Dis 44(2):256-62 (2007) |
| 100 | 2010 | Rare causes of calcitriol-mediated hypercalcemia: a case report and literature review. | 
| + | - | nl | J Clin Endocrinol Metab 95(7):3111-7 (2010) |
| 101 | 2011 | Viruses, autophagy genes, and Crohn's disease. | 
| + | - | nl | Viruses 3(7):1281-311 (2011) |
| 102 | 2009 | Genotyping for NOD2 genetic variants and crohn disease: a metaanalysis. | 
| + | - | nl | Clin Chem 55(11):1950-7 (2009) |
| 103 | 2011 | A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-α) inhibitors, adalimumab and infliximab, for Crohn's disease. | 
| + | - | nl | Health Technol Assess 15(6):1-244 (2011) |
| 104 | 2009 | Nutritional consequences and nutrition therapy in Crohn's disease. | 
| + | - | nl | Gastroenterol Clin Biol 33 Suppl 3(-):S235-44 (2009) |
| 105 | 2011 | Effect of adalimumab on work productivity and indirect costs in moderate to severe Crohn's disease: a meta-analysis. | 
| + | - | nl | Can J Gastroenterol 25(9):492-6 (2011) |
| 106 | 2005 | The anti-Saccharomyces cerevisiae antibody assay in a province-wide practice: accurate in identifying cases of Crohn's disease and predicting inflammatory disease. | 
| + | - | nl | Can J Gastroenterol 19(12):717-21 (2005) |
| 107 | 2007 | Frequency of epithelioid granulomas in colonoscopic biopsy specimens from paediatric and adult patients with Crohn's colitis. | 
| + | - | nl | J Clin Pathol 60(11):1268-72 (2007) |
| 108 | 2005 | Clinical value of gene NOD2/CARD15 mutations in Crohn's disease. | 
| + | - | nl | Rev Esp Enferm Dig 97(8):541-6 (2005) |