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SREBP
LE WE PMID CA
SREBP2603SREBP

3 HMG CoA reductase

Cholesterol

Ichthyosis follicularis alopecia photophobia (IFAP) syndrome

Insig

LXR

MBTPS2

Oxysterol

Scap

SREBP

2006  
1
SREBPs: sterol-regulated transcription factors.
[16525117] J Cell Sci 119(Pt 6): 973-6 (2006)
2000  
2
Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action.
[10934219] J Biol Chem 275(42): 32379-82 (2000)
2002  
3
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.
[11994399] J Clin Invest 109(9): 1125-31 (2002)
1997  
4
SREBPs, membrane lipid biosynthesis, and fatty acids.
[9378803] J Clin Invest 100(8): 1905-6 (1997)
2000  
5
Unsaturated fatty acids inhibit sterol regulatory element-dependent gene expression: a potential mechanism contributing to hypertriglyceridemia in fat-restricted diets.
[11082211] Proc Soc Exp Biol Med 225(3): 184-6 (2000)
2004  
6
Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins.
[15457548] World J Gastroenterol 10(21): 3081-7 (2004)
2006  
7
Protein sensors for membrane sterols.
[16413480] Cell 124(1): 35-46 (2006)
1997  
8
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor.
[9150132] Cell 89(3): 331-40 (1997)
2009  
9
Are side-chain oxidized oxysterols regulators also in vivo?
[18952574] J Lipid Res 50 Suppl(-): S213-8 (2009)
2009  
10
Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL.
[18974038] J Lipid Res 50 Suppl(-): S15-27 (2009)
2009  
11
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been.
[19933148] Genes Dev 23(22): 2578-91 (2009)
2009  
12
IFAP syndrome is caused by deficiency in MBTPS2, an intramembrane zinc metalloprotease essential for cholesterol homeostasis and ER stress response.
[19361614] Am J Hum Genet 84(4): 459-67 (2009)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.


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