SD208

LE WE PMID CA

SD208

2497

SD208

2006 1	Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression. [16707625] Mol Pharmacol 70(2): 518-31 (2006)
2005 2	Heart rate recovery after exercise: a predictor of ventricular fibrillation susceptibility after myocardial infarction. [15563535] Am J Physiol Heart Circ Physiol 288(4): H1763-9 (2005)
2007 3	Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness. [17400764] Mol Pharmacol 72(1): 152-61 (2007)
2006 4	Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-beta type I receptor kinase in vivo. [16857807] Clin Cancer Res 12(14 Pt 1): 4315-30 (2006)
2008 5	Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS. [18474728] Blood 112(8): 3434-43 (2008)
2008 6	Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. [18202349] Am J Respir Crit Care Med 177(8): 896-905 (2008)
2006 7	Effect of transforming growth factor-beta receptor I kinase inhibitor 2,4-disubstituted pteridine (SD-208) in chronic allergic airway inflammation and remodeling. [16888081] J Pharmacol Exp Ther 319(2): 586-94 (2006)
2007 8	Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta. [17468136] Am J Physiol Lung Cell Mol Physiol 293(1): L245-53 (2007)
2006 9	Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts. [16575856] Arthritis Rheum 54(4): 1309-16 (2006)
2004 10	SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo. [15520202] Cancer Res 64(21): 7954-61 (2004)
2004 11	Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment. [15569984] Clin Cancer Res 10(22): 7540-6 (2004)
2008 12	Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction. [18653707] Endocrinology 149(11): 5828-34 (2008)

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