Irinotecan

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Irinotecan

LE WE PMID CA

Irinotecan

1380

Irinotecan

Colon and rectum (Neoplasia)

Irinotecan

Oxaliplatin

Raltitrexed

UGT1A1

2008 1	The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer: systematic review and economic evaluation. [18462574] Health Technol Assess 12(15): iii-ix, xi-162 (2008)
1997 2	CPT-11 (irinotecan) in the treatment of colorectal cancer: a new mechanism of action for additional activity. [9154078] Tumori 83(1 Suppl): S85-6 (1997)
2002 3	Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity. [12453851] Ann Oncol 13(12): 1841-51 (2002)
2008 4	Irinotecan and uridine diphosphate glucuronosyltransferase 1A1 pharmacogenetics: to test or not to test, that is the question. [18720361] Cancer 113(7): 1502-10 (2008)
2001 5	Clinical pharmacokinetics and metabolism of irinotecan (CPT-11). [11489791] Clin Cancer Res 7(8): 2182-94 (2001)
2000 6	Insights into the pharmacokinetics and pharmacodynamics of irinotecan. [10999719] Clin Cancer Res 6(9): 3393-4 (2000)
2009 7	Irinotecan therapy and molecular targets in colorectal cancer: a systemic review. [19653336] World J Gastroenterol 15(29): 3597-602 (2009)
2010 8	Pharmacogenetics of irinotecan: An ethnicity-based prediction of irinotecan adverse events. [21160829] World J Gastrointest Surg 2(1): 14-21 (2010)
2009 9	Recommendations from the EGAPP Working Group: can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? [19125128] Genet Med 11(1): 15-20 (2009)
2009 10	Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review. [19125129] Genet Med 11(1): 21-34 (2009)

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