LE WE PMID CA
IAPP islet amyloid polypeptide11263IAPP islet amyloid polypeptide

beta cell (Pancreas)

Diabetes mellitus (Beta cell decay)

Endoplasmic reticulum (associated degradation)

ERS UFR (Apoptosis)

ERS UFR (Diseases)

IAPP islet amyloid polypeptide

Obesity (BASKET)

TRPV4

Ubiquitin

UCH L1

2011  
1
beta-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.
[20980462] Diabetes 60(1): 227-38 (2011)
2009  
2
Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.
[19151199] Diabetes 58(4): 906-16 (2009)
2007  
3
Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis.
[17563070] Diabetes 56(9): 2284-94 (2007)
2007  
4
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.
[17475933] Diabetes 56(8): 2016-27 (2007)
2008  
5
Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.
[18751967] Diabetologia 51(12): 2252-62 (2008)
2008  
6
Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus.
[18483616] Exp Diabetes Res 2008(-): 421287 (2008)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.



  • IAPP islet amyloid polypeptide

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