Fenretinide

LE WE PMID CA

Fenretinide

5982

Fenretinide

17 N allylamino 17 demethoxygeldanamycin

4 hydroxybenzylretinone

Apoptosis

Arsenic trioxide ttROS

Bacitracin ttPDI

Bortezomib ttProteasom

Caspase8

CD95 FAS Apo1

Ceramide

Chemoprevention

EIF2AK3 PERK

ERS UFR (Apoptosis)

ERS UFR (Induced Mediators)

ERS UFR (Pharmacology)

Fenretinide

Interleukin24 MDA7

JNK

Kidney (Neoplasia RCC)

Neoplasia (Oncolytic virus)

P4HB procollagen proline 2 oxoglutarate 4 dioxygenase beta subunit

PLAB placental bone morphogenetic proteinPLAB

Protein disulfide isomerase

Salubrinal

SP600125 ttJNK1 ttJNK2 ttJNK3

2006 1	Fenretinide in the prevention of breast cancer in premenopausal women: fluke or fact? [16766581] Ann Oncol 17(7): 1035-6 (2006)
2004 2	Fenretinide activates a distinct apoptotic pathway. [15339958] J Natl Cancer Inst 96(17): 1264-5 (2004)
1999 3	Fenretinide: the death of a tumor cell. [10393709] J Natl Cancer Inst 91(13): 1099-100 (1999)
1994 4	Prospects of chemoprevention of human cancers with the synthetic retinoid fenretinide. [8137334] Cancer Res 54(7 Suppl): 2032s-2037s (1994)
2011 5	A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. [21119025] Mol Pharmacol 79(3): 368-80 (2011)
2008 6	Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress. [18593938] Cancer Res 68(13): 5363-9 (2008)
2007 7	The unhydrolyzable fenretinide analogue 4-hydroxybenzylretinone induces the proapoptotic genes GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis that is caspase- dependent and independent of the retinoic acid receptor. [17616685] Cancer Res 67(13): 6270-7 (2007)
2009 8	PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation. [19325135] Carcinogenesis 30(5): 824-31 (2009)
2009 9	The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response. [19228726] Clin Cancer Res 15(4): 1199-209 (2009)
2009 10	Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma. [19228725] Clin Cancer Res 15(4): 1192-8 (2009)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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