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Drotrecogin alpha
LE WE PMID CA
Drotrecogin alpha725Drotrecogin alpha

Drotrecogin alpha

Sepsis

2003  
1
Role of activated protein C in the pathophysiology of severe sepsis.
[14619357] Am J Crit Care 12(6): 518-24; quiz 525-6 (2003)
2008  
2
Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated).
[18394162] Crit Care 12(2): R45 (2008)
2007  
3
Practical aspects of treatment with drotrecogin alfa (activated).
[18269694] Crit Care 11 Suppl 5(-): S7 (2007)
2007  
4
The safety profile of drotrecogin alfa (activated).
[18269693] Crit Care 11 Suppl 5(-): S6 (2007)
2007  
5
Clinical trials in severe sepsis with drotrecogin alfa (activated).
[18269692] Crit Care 11 Suppl 5(-): S5 (2007)
2007  
6
The protein C pathway: implications for the design of the RESPOND study.
[18269691] Crit Care 11 Suppl 5(-): S4 (2007)
2007  
7
Recombinant human activated protein C: current insights into its mechanism of action.
[18269690] Crit Care 11 Suppl 5(-): S3 (2007)
2007  
8
Recombinant activated protein C in sepsis: endothelium protection or endothelium therapy?
[17224039] Crit Care 11(1): 103 (2007)
2003  
9
Clinical review: Drotrecogin alfa (activated) as adjunctive therapy for severe sepsis--practical aspects at the bedside and patient identification.
[14624684] Crit Care 7(6): 445-50 (2003)
2007  
10
Drotrecogin alfa (activated) in severe sepsis: a systematic review and new cost-effectiveness analysis.
[17592639] BMC Anesthesiol 7(-): 5 (2007)
2006  
11
Treatment of severe sepsis: where next? Current and future treatment approaches after the introduction of drotrecogin alfa.
[17319465] Vasc Health Risk Manag 2(1): 3-18 (2006)
2009  
12
Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies.
[19774207] Biologics 3(-): 391-406 (2009)
2005  
13
Clinical effectiveness and cost-effectiveness of drotrecogin alfa (activated) (Xigris) for the treatment of severe sepsis in adults: a systematic review and economic evaluation.
[15774234] Health Technol Assess 9(11): 1-126, iii-iv (2005)
2009  
14
Modulation of sepsis outcome with variants of activated protein C.
[19630784] J Thromb Haemost 7 Suppl 1(-): 127-31 (2009)
2007  
15
2004  
16
2003  
17
Drotrecogin alfa (activated): a novel therapeutic strategy for severe sepsis.
[12566544] Postgrad Med J 79(927): 5-10 (2003)
2009  
18
Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study.
[19696442] Am J Respir Crit Care Med 180(9): 861-6 (2009)
2007  
19
Activated protein C: cost-effective or costly?
[17875223] Crit Care 11(5): 164 (2007)
2009  
20
Treatment of septic shock and use of drotrecogin alfa (activated) in children.
[19735218] Expert Rev Anti Infect Ther 7(7): 769-72 (2009)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.


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