LE WE PMID CA
BiP GRP789288BiP GRP78

Apoptosis

Bim

BiP GRP78

Cell stress (ER stress)

eIF2A

Endoplasmic reticulum (BASKET)

GADD34

Interleukin24 MDA7

IRE1alpha

Leukemia (acute myeloic)

MCL1

Noxa

Unfolded protein response

2010  
1
Life and death of a BiP substrate.
[20026282] Semin Cell Dev Biol 21(5): 472-8 (2010)
2006  
2
BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.
[16912197] Cancer Res 66(16): 8182-91 (2006)
2010  
3
Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.
[20858700] Mol Pharmacol 78(6): 1096-104 (2010)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.



  • BiP GRP78

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