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-/- 2020; 13 (4): 4-7


Allergiebehandlung und COVID-19.

-/- 2020; 36 (6): 66


Organspende: Noch zu hufig entscheiden Angehrige.

-/- 2020; 36 (6): 10-1


Springer Medizin zeichnet beste Innovationen aus.

-/- 2020; 36 (6): 59


Ist digital wirklich besser als analog?

-/- 2020; 22 (11): 3


Springer Medizin zeichnet beste Innovationen aus.

-/- 2020; 36 (6): 15


Bei Kindern Trigger gezielt abfragen!

-/- 2020; 36 (6): 41


Corona - das Schlachtfeld des 21. Jahrhunderts?

-/- 2020; 36 (6): 48-9


Lang bestehende Hautmanifestationen.

-/- 2020; 36 (6): 10


Corona steigert Praxiskosten.

-/- 2020; 36 (6): 12


"Wir finden keine massiven Schden an Neuronen".

-/- 2020; 22 (11): 6-7


Aktuelle Updates zu COVID-19.

-/- 2020; 36 (6): 8


Wir sind online - Sie auch?

-/- 2020; 36 (6): 38-9


Lehren und Chancen fr Anleger.

-/- 2020; 36 (6): 66


Examining privilege and power in US urban parks and open space during the double crises of antiblack racism and COVID-19.

-/- ; (): 1-16

In this perspective, we argue that creating the positive outcomes socio-ecological researchers and practitioners seek for urban areas requires acknowledging and addressing the interactions of race and systemic racism in parks, open and green spaces. Racial experiences are inseparable from physical landscapes and the processes of designing, managing, or studying them. From COVID-19 to the Black Lives Matter movement and protests, the events of 2020 in the United States underscore how considerations of social justice must extend beyond the conventional distributional focus of environmental justice. It must incorporate an understanding of how the built environment is racialized spatially, but not always readily quantified through the proximity-based measurements frequently used in research and practice. The perspective is organized in three main parts. The first part presents a series of vignettes to frame the ways cities and individuals participate, respond, and interact under COVID-19 with racial segregation as the backdrop. The second part suggests a stepwise approach to building an understanding of racial inequities in socio-ecological systems (SES) research and practice including four entry points: (1) racialized spatial distribution of hazards and amenities, (2) racialized qualities of space, (3) racialized people in space, and (4) racialized creation of space. Finally, the third part proposes actions the SES community can take to enhance our commitment to community recovery, improvement, and thrivability. This perspective cautions practitioners and researchers against opportunistic or quick-fix solutions, and instead challenges our colleagues to be inclusive of disenfranchised voices in shaping socio-ecological goals, now more than ever. The goal of this perspective is to spark engagement with power and privilege in parks and open space using the example of COVID-19 and race in the US.


Sportkonomische Auswirkungen der COVID-19-Pandemie am Beispiel der Fuball-Bundesligen.

-/- ; (): 1-13

In addition to significant global consequences, the COVID-19-Pandemia has also had massive impact on sports in general and professional soccer in particular. This paper highlights the significant consequences the pandemic has had for professional soccer in Germany. This is done by first briefly sketching the general effects of the pandemic before the consequences on German professional soccer are presented in more detail. Based on the basic conditions and specifics of the team sports industry, possible solutions to the problems are discussed. It is shown that specific support schemes from within the industry, such as solidarity funds and self-regulating measures, may have clear advantages over proposed state subsidies.


Philosophical reflections about the virtual world.

-/- ; (): 1-11

Changes in the operating ambience is normally welcome. But the change world is facing is accompanied by an unacceptable reason called Covid virus spread. However, educational institutions, while observing the norms imposed by various administrations, have managed to do an excellent job of ?teaching? against the odds. Moreover, everyone was caught by surprise. Overnight the world changed. We decided to understand the reactions from our faculty to the challenge arising out of Covid, and also use of terminologies such as online, virtual, reality, perception, understanding, and so on. The result is this paper, which is a collection of ?reactions?.



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COVID-19: Harbinger of a New Psychology of Religion for Postcolonial Societies.

-/- ; (): 1-13

Religious practice, like every other human affair, was altered at the onset of the pandemic. The paper argues that the ?home church? as a Christian expression of religiosity during Covid-19, for instance, was a signal to something new at least in the theoretical realms of religion. More strongly, it was a vindication of postcolonial native societies (of Africa) whose indigenous spiritualities were thwarted and/or abolished during the colonial era. The pandemic is theorized as a wake-up call for agency in these societies. The theorization relies upon Piaget?s psychological ?techniques? of accommodation and assimilation, opening various channels to answering the questions: what was assimilated during colonialism that should have been accommodated and vice versa? And how has the pandemic uncovered that error of inversion?


Collective Editorial: Ten Guidelines for Strategic Social Action.

-/- ; (): 1-16


New technologies used in COVID-19 for business survival: Insights from the Hotel Sector in China.

-/- ; (): 1-8

The tourism industry is in a fight for survival during the coronavirus pandemic. This essay was written based upon several interviews conducted with directors and general managers of nine well-known hotels in China with the aim to investigate what new technologies are used to mitigate the impact of the pandemic. DeLone and McLean?s Information System Success Model was applied to examine the adopted digital technologies. Live-stream promotion and live-stream conference are introduced to primarily improve information quality, while 5G technology and Wi-Fi 6 are installed to enhance the system quality. Facial recognition, AI, and Robots are integrated to the daily operations to enhance service quality. Challenges and future directions are discussed.


Marketing in the era of COVID-19.

-/- ; (): 1-12

We discuss the effects of COVID-19 on consumer behaviour and elaborate on the consequences of this disruption for marketing strategies and marketing policies. The crisis shows similarities with changes in consumer behaviour and the way marketing is carried out during economic downturns. However, it also displays characteristics which differ from downcycles, such as shifts in consumption between categories and the accelerated shift from offline to online behaviour. This is forced by the re-evaluation of life priorities by final consumers.


Evaluation of real-time tracheal ultrasound versus colorimetric capnography as a point of care tool for confirmation of endotracheal intubation: a randomized controlled study.

-/- 2020; 12 (1):

Background: Endotracheal intubation is essential for optimal airway control during general anesthesia or resuscitation of critically ill patients. Misplacement of the endotracheal tube (ETT) can lead to devastating, preventable morbidity and mortality. Colorimetric carbon dioxide detectors are considered a simplistic mainstream capnography that contains a pH-sensitive chemical marker that is prone to color change with ventilation. Real-time tracheal ultrasound allows for the dynamic observation of tube passage through the trachea or the esophagus, providing immediate confirmation of placement prior to any ventilation attempts with reported sensitivity/specificity of 100% for adult patients in the operating room.We aimed to compare two different techniques (tracheal real-time ultrasound vs colorimetric capnography) as point of care tools for confirmation of correct endotracheal tube position. Results: This study carried out on eligible seventy patients undergoing general anesthesia. Patients were divided randomly and equally into two groups (35 patients each). Group A in which patients? ETT position was confirmed by real-time tracheal ultrasound and group B in which patients? ETT position was confirmed by colorimetric capnography. Comparing both groups according to their diagnostic performance for detecting the correct position of the ETT inserted showed the diagnostic sensitivity, specificity, and accuracy of real-time tracheal ultrasound vs colorimetric capnography (93.8%, 66.7%, and 91.4% VS 97%, 50%, and 94.3% respectively). Although there were higher sensitivity and accuracy of colorimetric capnography than real-time tracheal ultrasound, the p value between the two groups was 0.462. Conclusion: Both tools are fast, effective, reliable, and accurate with many advantages and few disadvantages including the need for training on ultrasound practice and air-filled stomach in colorimetric capnography. However, these disadvantages can be easily overruled and the benefits from both tools overweigh their disadvantages.


Municipal waste Management in the era of COVID-19: Perceptions, Practices, and Potentials for Research in Developing Countries.

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The novel COVID-19 pandemic has significantly impacted all facets of society globally. Often overlooked is the potential contamination of the waste disposed by individuals diagnosed with the virus. The proliferation of contaminated waste is expected to increase as cases increase. The pandemic has caused a surge in waste material stemming from the widespread use of disposable personal protective equipment at the household level. In the developing countries where waste management measures are relatively inadequate, the vulnerability of COVID-19 contraction from contaminated waste is high. This study intended to unravel the susceptibility of communities in the developing countries of Guyana and Nigeria to the potential spread of the virus through waste. The study explored the possibility of cross-contamination between residents and landfill scavengers, the community perception on the effectiveness of their solid waste practices, the notable changes in waste collection and waste disposal patterns, and also, the potential knowledge / policy gaps that exist. An online survey was administered within all the districts of the two countries and the qualitative assessment was conducted demonstrating the proportional trends in the responses of the participants. Findings showed that the communities were relatively perceptive about the issue of waste disposal and the potential contamination of COVID-19. The communities readily recognized the inefficiencies of the waste management systems and the need for policy intervention. Tackling the issue of COVID-19 and waste management in the developing countries of Guyana and Nigeria requires policies that are holistic and participatory involving stakeholder at all levels.


Krebsprvention im Fokus.

-/- 2020; 35 (6): 439


An imperialist competition algorithm using a global search strategy for physical examination scheduling.

-/- ; (): 1-16

The outbreak of the novel coronavirus clearly highlights the importance of the need of effective physical examination scheduling. As treatment times for patients are uncertain, this remains a strongly NP-hard problem. Therefore, we introduce a complex flexible job shop scheduling model. In the process of physical examination for suspected patients, the physical examiner is considered a job, and the physical examination item and equipment correspond to an operation and a machine, respectively. We incorporate the processing time of the patient during the physical examination, the transportation time between equipment, and the setup time of the patient. A unique scheduling algorithm, called imperialist competition algorithm with global search strategy (ICA_GS) is developed for solving the physical examination scheduling problem. A local search strategy is embedded into ICA_GS for enhancing the searching behaviors, and a global search strategy is investigated to prevent falling into local optimality. Finally, the proposed algorithm is tested by simulating the execution of the physical examination scheduling processes, which verify that the proposed algorithm can better solve the physical examination scheduling problem.


Revisiting international human rights treaties: comparing Asian and Western efforts to improve human rights.

-/- 2021; 1 (1):

This paper presents a review of existing literature to understand the effects and effectiveness of human rights treaties in the Asia Pacific region, particularly in Southeast Asian countries, in contrast to Western nations. The review argues that factors at the international/treaty level and factors at the domestic state level increase the difficulty of implementing effective international treaties on human rights. At the international level, the treaties and organizations to which states belong suffer some weakness as discussed in international relations theories, while seven factors are particularly important for promoting effectiveness of international human rights treaties at the domestic level: political capacity, economic development, national human rights institutes, regional human rights courts, regional intergovernmental organizations, strength of civil society, and political stability. Although the number of international human rights agreements signed and ratified by Asia Pacific states is increasing following the trends of Western states, less research focuses on the implementation and effects of these institutions. Asia Pacific nations face vastly different conditions than Western nations, such as more complicated security environments, larger cultural and religious differences, and less development and democratic values in some cases. Due to these differences, it is important to consider other potential variables that influence efficacy of treaty instruments for non-Western nations. What are the differences between implementation of human rights treaties in Western and Asian nations? How do they affect the efficacy of international agreements on individual human rights?


Why Are Patients With COVID-19 at Risk for Drug-Drug Interactions?

-/- 2020; 26 (6): 485-92

The goal of this column is to provide information to health care professionals about drug-drug interactions (DDIs) and why DDIs are important to consider in those at serious risk of illness with Coronavirus Disease 2019 (COVID-19). Important considerations discussed in this column include the frequency and complexity of multiple medication use, particularly important for the older patient who often has multiple comorbid illnesses. The column covers the following issues: (1) Why patients at high risk for serious illness from COVID-19 are also at high risk for DDIs. (2) Application of results of pharmacoepidemiological studies to the population at risk for serious COVID-19 illness. (3) Mechanisms underlying DDIs, frequency and potential complexity of DDIs, and how DDIs can present clinically. (4) Methods for preventing or mitigating DDIs. (5) An introduction to the University of Liverpool drug interaction checker as a tool to reduce the risk of adverse DDIs while treating patients for COVID-19. Commentary is also provided on issues related to specific psychiatric and nonpsychiatric medications a patient may be taking. A subsequent column will focus on DDIs between psychiatric medications and emerging COVID-19 treatments, as a detailed discussion of that topic is beyond the scope of this column.


Wissenschaftskommunikation zwischen Gesellschafts?, Wissenschafts- und Medienwandel.

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3D-printed shields for slit lamps produced during the COVID19 pandemic.

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Additive manufacturing has been extensively used during the COVID19 pandemic to design and produce protection equipment. During clinical examinations using slit lamps, ophthalmologists are at risk of being contaminated, and the device itself is exposed to viral contamination. Several solutions have already been proposed for fixing transparent shields on the physician?s side. Here we propose a 3D printed device fixed on the chin rest on the patient?s side, aiming at limiting viral spread both on the lamp itself and towards the physician.


La Direction des Affaires Juridiques et des Droits des Patients de l?APHP et la premire vague de la pandmie Covid-19.

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To facilitate the analysis and the management of claims related to the last Covid19 pandemic, the DAJ of the APHP constituted a medical group assisted by lawyers intending to review the scientific knowledge and organizational measures during the first wave of this pandemic.This group brought together medical doctors with both scientific expertise in the main specialties requested during this viral infection and knowledge of repairing bodily damage. Based on the data provided by the hospital dashboards and the collection of hospital procedures for Covid-19 and non-Covid-19 patients, the goal of this group was to assess the level of scientific knowledge and organizational measures respectively at the start of the epidemic, its peak and at the end. During the three periods of this pandemic the main changes observed included a greater selectivity on admissions with increasing consideration on the patient?s comorbidity; a continual evolution in drug management and more rigorous isolation measures with interruption of visiting rights. The target was to prevent contamination of the non-infected persons with an obsession to protect healthcare workers. The absence of selection for patients requiring intensive care for compensation of their respiratory failure forced APHP to double the number of intensive care beds and to refer some patients in other regions. In a context of unstable scientific knowledge and evolving organizational measures, the collection of these data should facilitate the management of claims related to Covid19 during the first wave of this pandemicand open a prospective study for the next pandemic.


3D-printed suture guide for thoracic and cardiovascular surgery produced during the COVID19 pandemic.

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Emergency 3D-printing of medical devices came out as a potential solution to tackle shortages during the COVID-19 pandemic. Manufacturing medical devices in small series within hospital is an exciting perspective in crisis management. Health professionals and additive manufacturing technology are ready for this revolution but regulative adaptations are still required. Here we present the design and production of a suture guide for cardiac surgery as a case study for a 3D printed medical device manufactured during the COVID-19 pandemic.


The Social Group Distinction of Nationalists and Globalists amid COVID-19 Pandemic.

-/- ; (): 1-19

The primary discussion in this article is the classification of the typical reactions of social groups in various nations as nationalist and globalist. Subject to the new coronavirus pandemic, nationalists have adopted extreme national security policies, namely, ?the nation?s interests prevails;? globalists have adopted moderate policies by complying with the faith of society in the recommendations of the scientific community. The disparate contrasts in values and actions between the two groups are extensively manifested in domestic disease control, attitude toward the World Health Organization, identification of the disease?s source, vaccine research, international cooperation, and social reaction. This research indicates that nationalists largely consist of conservative country leaders, ?social elites,? populists, and individuals in the middle-lower class, many of whom uphold racism and extreme nationalism, and that globalists largely consist of international organizations and regional leaders, medical practitioners, intellectuals and philanthropic entrepreneurs, the middle-upper class population. This social group distinction is clarified in accordance with converse ethical value perspectives, ideologies, social group-economic interests, and even national competition positions. Regarding cultural and institutional basics, nationalists uphold neoliberalism, social Darwinism, the law of jungle, and individualism, whereas globalists advocate for social democracy and collectivistic ethnic codes. The two parties have been competing for the high moral ground during and the pandemic, thereby profoundly affecting the relationships of nations worldwide.


Natural and Synthetic Drugs as Potential Treatment for Coronavirus Disease 2019 (COVID-2019).

-/- ; (): 1-13

Coronavirus disease 2019 (COVID-19) has become a global pandemic in a short period, where a tragically large number of human lives being lost. It is an infectious pandemic that recently infected more than two hundred countries in the world. Many potential treatments have been introduced, which are considered potent antiviral drugs and commonly reported as herbal or traditional and medicinal treatments. A variety of bioactive metabolites extracts from natural herbal have been reported for coronaviruses with some effective results. Food and Drug Administration (FDA) has approved numerous drugs to be introduced against COVID-19, which commercially available as antiviral drugs and vaccines. In this study, a comprehensive review is discussed on the potential antiviral remedies based on natural and synthetic drugs. This review highlighted the potential remedies of COVID-19 which successfully applied to patients with high cytopathic inhibition potency for cell-to-cell spread and replication of coronavirus.


COVID-19, instability and migrant fish workers in Asia.

-/- ; (): 1-13

This paper seeks to establish how COVID-19 is impacting migrant fish workers through focusing on two global fish hubs, Thailand and Taiwan. Through a careful review of the news reports, social media, and NGO reports and press releases, three significant themes emerged: employment disruptions due to seafood system instabilities; travel or mobility restrictions; and poor access to services such as health care or social programs. We unpack each theme in turn to spotlight the impacts COVID-19 is having on yet another vulnerable worker population, fish workers. We further reflect on what this pandemic reveals about unacceptable work in industrial fisheries and consider if the pandemic may be producing opportunities to advocate for better working conditions.


Introduction to the Special Issue: COVID-19 and Its Impact on Racial/Ethnic Groups.

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Global crop waste burning ? micro-biochar; how a small community development organization learned experientially to address a huge problem one tiny field at a time.

-/- 2020; 3 (1):

The world?s 2.5 billion poorest people - small farmers living at the far fringe of the developing world ? and their billion or so slightly better off neighbors burn 10.5 billion metric tonnes (tonnes) of crop waste annually. Smoke from their fires reddens the sun, closes airports, shuts schools and governments ? and kills millions of people (World Health Organization (WHO). Their fires release 16.6 billion tonnes of CO2, and emit 9.8 billion tonnes CO2e, 1.1 billion tonnes of smog precursors and 66 million tonnes of PM2.5. (Akagi et al., Atmospheric Chem Physics 4039-4071, 2011; Environmental Protection Agency,; Food and Agriculture Organization, FAOSTAT, [See Attachments 1?3. For details of the Attachments, please see the section below entitled ?Availability of data and materials.?]. No one yet has stopped the burning. Seminars, health warnings, bans, threats, jailings, shootings ? nothing has worked, because not one has offered farmers a better alternative. This is the story of how Warm Heart, a small, community development NGO, learned enough about small farmers? plight to collaborate with them to develop the technology, training and social organization to mobilize villages to form biochar social enterprises. These make it profitable for farmers to convert crop waste into biochar, reducing CO2e, smog precursor and PM2.5 emissions, improving health and generating new local income ? in short, to address the big three SDGs (1, 2 and 3) from the bottom.Warm Heart, however, wanted more; it wanted a system so appealing that it would spread by imitation and not require outside intervention. Based on what it has learned, Warm Heart wants to teach others that the knowledge to stop the smoke and improve the quality of one?s life does not require outside experts and lots of money. It wants to teach that anyone can learn to create a more sustainable world by themselves.This article traces the experiential learning process by which Warm Heart and its partners achieved their goals and shares Warm Heart?s open source solution. It serves four purposes. The article closely explores an experiential learning process. It details the underlying logic, workings and consequences of crop waste burning in the developing world. It demonstrates the application of this knowledge to the development of a sustainable ? even profitable ? solution to this global problem that does not require costly outside intervention but can be undertaken by local communities and small NGOs anywhere. Finally, it models how local communities, small NGOs and social investors can turn this global problem into a profitable business opportunity.


Coaching self-defense under COVID-19: challenges and solutions in the police and civilian domain.

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The spread of SARS-CoV-2 has led to a general shutdown of police and civilian self-defense training. While means of distance learning such as online teaching appear to be feasible for theory dominant subjects addressing cognitive resources of the learner, combat-related practices like self-defense trainings dont seem to fit into the realm of virtual learning due to their bodily foundation. This is made clear by the collective perplexity of police and civilian coaches, gyms and organizations, on how to proceed with training during the lockdown in general, while approaches of distance learning (e.g., online learning) have rarely been considered. In the following article, we tackle the situation of police and civilian self-defense coaches in times of Corona. In a first step, contextual changes and challenges of coaching self-defense are identified through the lenses of a professional coaching model. In line with basic assumptions of ecological dynamics, adaptability seems to be the decisive resource for the coaching and training of self-defense in times of Corona. As an example for such an adaptation in training practice, a conceptual framework for distance-based self-defense training in the civilian and police domain is presented. This framework is adjusted to the respective requirements of physical distancing and adopted to novel security matters within the public sphere caused by the current regulations. In sum, the article attempts to provide ideas and orientation for police and civilian self-defense coaches as well as for their own development possibilities.


Complexity in China?s current role in multilateral orders.

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Rather than the prescribed scenario of a Thucydides Trap or a Kindleberger Trap, the global system will see a Transitional Reformation process of contestation and cooperation as power transitions from North America and Europe towards Asia and other regions. While acknowledging that power increasingly diffuses from state actors to transnational civil societies and private sectors, this article contends that, in a state-centric global system, it remains significant that US?China competition, and the wider competition, contestation and renegotiation of power relations between established and rising powers, takes place within United Nations multilateral frameworks. In addressing China?s role, potential, and limits in the dynamics of renegotiation, this article identifies three layers, or subprocesses,of complexity in the current role China plays in multilateral orders in flux.


Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19.

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Aims: To define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA). Materials and methods: We performed a single-center retrospective study of IHCA cases. Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year. Return of spontaneous circulation (ROSC), 30-day survival, and cerebral performance category (CPC) at 30-days were assessed. Results: Fifty-five patients with COVID-19 suffering IHCA were identified and compared to 55 consecutive IHCA patients in 2019. The COVID-19 cohort was more likely to require vasoactive agents (67.3% v 32.7%, p?=?0.001), invasive mechanical ventilation (76.4% v 23.6%, p?


Despite the Virus, the Special Issue for the 16th Pegasus Student Conference.

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Hydroxychloroquine/tocilizumab: Cytomegalovirus enterocolitis and hypovolaemic-shock following off-label use: case report.

-/- 2020; 1831 (1): 149


Drug-drug interactions in patients with COVID-19.

-/- 2020; 1831 (1): 8


Enoxaparin sodium/methylprednisolone: Cytomegalovirus reactivation, gastrointestinal haemorrhage and off-label use: case report.

-/- 2020; 1831 (1): 131


Multiple drugs: Neutropenia and COVID-19 infection: 4 case reports.

-/- 2020; 1831 (1): 208


Immunosuppressants: Haematological disorders and COVID-19: 2 case reports.

-/- 2020; 1831 (1): 156


Azithromycin/hydroxychloroquine: Cardiac disorder followed by off-label use: case report.

-/- 2020; 1831 (1): 75


Imatinib: Rhabdomyolysis: case report.

-/- 2020; 1831 (1): 152


Multiple drugs: Various toxicities and off label use: 3 case reports.

-/- 2020; 1831 (1): 213


Covid-19 Pandemic: Need to Exercise Caution While Using Hypochlorite Sanitizer in Manufacturing Industries.

-/- ; (): 1-3

World is fighting Covid-19 pandemic since beginning of the year 2020. To prevent spread of Covid-19 disease, sanitization of workplaces using sodium hypochlorite (NaOCl) disinfectant is one of the several precautionary steps that are followed currently. In this letter, I share an experience wherein regular spraying of NaOCl solution in metal forming section of an organization led to development of corrosion damage and rejection of a large number of aircraft structural components made of Al-2024 alloy sheet material.


Pandemic-Related Perceived Stress Scale of COVID-19: An exploration of online psychometric performance?.

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Porqu es menos "intensa" la epidemia de Covid-19 en frica??.

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Most of the international bibliography published on Covid-19 pandemics is focused in the Asian, European or American continents. It seems that incidence is lower in Africa. In this article we hypothetize on several of the possible causes sustaining these differences. Population pyramid, climate, african population own vulnerability/resistance or sociopolitical factors are underlined.In the case the pandemics will spread in Africa, the lack of basic healthcare resources will perhaps make the consequences disastrous and of a dantesque magnitude.


Encefalitis viral por Covid 19: Reporte de caso.

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Different viruses have been identified at various times, such as Epstein-Barr, cytomegalovirus, herpes simplex 1-2, and human immunodeficiency virus. These have harmful effects on the central nervous system, causing temporary or permanent alterations in its functions. Previous reports arising from the SARS of 2002 and the MERS-COV of 2012, suggest that the coronavirus has an atypical presentation of neurological compromise, since it has a neuro-invasive and neurotropic capacity, and can cause polyneuropathies, seizures, psychosis or promote cerebrovascular accidents. A case is also reported in which there was a high suspicion of acute encephalitis due to SARS CoV2.



-/- ; ():

In March 2020,?the World Health Organisation declared a SARS-CoV-2 pandemic. Since then, many articles have shown it to have a mild to moderate course in most of infected children. However, few patients may develop a???hyper-inflammatory syndrome with shock and multisystemic compromise, all clinical features similar to?Kawasaki Disease ? and Toxic Shock Syndrome. This clinical pattern has been designated by the Centre of Disease Control (CDC) as a multisystemic inflammatory syndrome in children (MIS-C). It has been seen in previously healthy children, or those with comorbidities of active or recent coronavirus disease, or close contact with a COVID?19 infected patient.A case is reported of MIS-C, with signs of distributive shock and multisystemic organ failure. Clinical features?and treatment are described. Severe neurological compromise and central nervous system bleeding are the clinical manifestations to highlight in this patient, which are poorly described in paediatric cases as a potentially fatal complication. A narrative review was carried out on the literature available. To the best of our knowledge, this is the first case of MIS-C published?in Colombia


Psychological impact of social isolation on the comorbid patient: on the subject of the COVID-19 pandemic.

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Coronavirus Disease Outbreak and Supply Chain Disruption: Evidence from Taiwanese Firms in China.

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Observing willingness of obtaining the influenza vaccine during and after COVID-19 Flu vaccination and COVID-19.

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Delegation of implementation in project aid.

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In this paper we explore the factors that determine delegation of implementation in project aid. In particular, focusing on the importance of informational asymmetry between levels of government, we empirically assess whether this choice is influenced by the relative importance of the local information at the recipient country level. Moreover, we test whether this choice can in turn influence project performance. Using information on more than 5800 World Bank projects for the period 1995-2014, and controlling for characteristics at both country and project level, we find that transparency does influence the probability that a project is implemented locally rather than nationally. More specifically, a one standard deviation decline in transparency increases the probability of a locally implemented project by three percentage points. We also find that a local implementing agency may increase the probability of a successful project only up to a certain level of a country?s transparency.Electronic supplementary material: The online version of this article (10.1007/s11558-020-09396-9) contains supplementary material, which is available to authorized users.


Peaks of Fine Particulate Matter May Modulate the Spreading and Virulence of COVID-19.

-/- ; (): 1-8

A probe of a patient, seeking help in an emergency ward of a French hospital in late December 2019 because of Influenza like symptoms, was retrospectively tested positive to COVID-19. Despite the early appearance of the virus in Europe, the prevalence and virulence appeared to be low for several weeks, before the spread and severity of symptoms increased exponentially, yet with marked spatial and temporal differences. Here, we compare the possible linkages between peaks of fine particulate matter (PM2.5) and the sudden, explosive increase of hospitalizations and mortality rates in the Swiss Canton of Ticino, and the Greater Paris and London regions. We argue that these peaks of fine particulate matter are primarily occurring during thermal inversion of the boundary layer of the atmosphere. We also discuss the influence of Saharan dust intrusions on the COVID-19 outbreak observed in early 2020 on the Canary Islands. We deem it both reasonable and plausible that high PM2.5 concentrations?favored by air temperature inversions or Saharan dust intrusions?are not only modulating but even more so boosting severe outbreaks of COVID-19. Moreover, desert dust events?besides enhancing PM2.5 concentrations?can be a vector for fungal diseases, thereby exacerbating COVID-19 morbidity and mortality. We conclude that the overburdening of the health services and hospitals as well as the high over-mortality observed in various regions of Europe in spring 2020 may be linked to peaks of PM2.5 and likely particular weather situations that have favored the spread and enhanced the virulence of the virus. In the future, we recommended to monitor not only the prevalence of the virus, but also to consider the occurrence of weather situations that can lead to sudden, very explosive COVID-19 outbreaks.


Azithromycin/hydroxychloroquine: Torsade-de-pointes following off-label use: case report.

-/- 2020; 1831 (1): 76


Multiple drugs: Lymphocytopenia and off-label use: case report.

-/- 2020; 1831 (1): 207


Tocilizumab: Decrease in WBC count following an off-label use: case report.

-/- 2020; 1831 (1): 270


Lopinavir/ritonavir/remdesivir: Drug induced liver injury and off label use: 5 case reports.

-/- 2020; 1831 (1): 183


Immunosuppressants: Hepatotoxicity, neutropenia and COVID-19 pneumonia : case report.

-/- 2020; 1831 (1): 157


Multiple drugs: Caecal haemorrhagic ulceration, cytomegalovirus infection and off-label use: case report.

-/- 2020; 1831 (1): 202


Multiple drugs: Pancytopenia, COVID-19 and off-label use: case report.

-/- 2020; 1831 (1): 209


Utilisation d?Airtraq pour l?intubation orotrachale pendant la pandmie par le SARS-CoV-2.

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Impact du confinement sur la sant des personnes ges durant la pandmie COVID-19.

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COVID-19infection entails a high risk of morbidity and mortality among the elderly, but the lockdown measures that are applied to limit the spread of the virus can also lead to potentially serious complications among the elderly. Three complications seem particularly important to us: sarcopenia, depression and delays in the treatment of chronic pathologies, such as cardiovascular or neoplastic diseases. We conducted a review of the literature on these three complications.


Tele-counselling for management of Chittodvega (anxiety disorder) in Ayurveda--composing ancillary methods during the Covid 19 pandemic.

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Corona Virus Disease (Covid 19) is a highly infectious disease declared as pandemic by WHO. Due to its fast spreading nature this is creating a threatening situation throughout the world. Breaking the chain of transmission by keeping social distancing along with maintaining strict personal hygiene is the only way to control the spread of the disease. The panic situation created by the disease along with the unfamiliar way of conduct imposed several psychological issues on human beings. Chittodvega (Anxiety disorder) is one among the commonly found psychological problem during this pandemic. An important modality called psychotherapy, mentioned in Ayurveda i.e. Satvavajaya chikitsa can be adopted in such situation. Tele-counselling which is coming under indirect counselling helps to handle the needy people with psychological issues, without directly approaching the medical practitioner during lockdown situation. Different modalities of Satvavajaya chikitsa which are similar to the steps of tele-counselling helps in providing medical management also.



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An untraditional start to my degree.

-/- 2020; 7 (10): 12-3


A degree for dental nurses.

-/- 2020; 7 (10): 9-10


Medical emergencies in the dental practice poster: revised and updated.

-/- 2020; 7 (10): 38-46


BDA leads call for plasma donations to fight COVID-19.

-/- 2020; 7 (10): 5


My passion to progress in dentistry.

-/- 2020; 7 (10): 30-1


Becoming successful dental therapists in challenging times.

-/- 2020; 7 (10): 28-9


Standardisierte Ortungsdaten fr die Produktion und Logistik.

-/- 2020; 7 (3): 66


Klares Profil bis zum Schluss.

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Aus der Branche.

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Events calendar.

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Recommendations for acting in elective and urgent thoracic surgery during SARS-CoV-2 pandemic. Spanish Society of Thoracic Surgery?.

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Teaching Chemical Engineering to Biotechnology students in the time of COVID-19: assessment of the adaptation to digitalization.

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?Cooperative learning as a consistent response to the closure derived from COVID-19.?Learning sequence promoting higher-order thinking competences and learning results.?Participation and motivation were fostered by means of the innovative methodology proposed.


Impact of the COVID-19 pandemic on the surgical activity of Pediatric Urology: analysis of postoperative complications according to the Clavien-Dindo classification?.

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Introduction and objective: The "Coronavirus Disease 2019" (COVID-19) has caused a pandemic of global impact that forced social-political measures to be taken, such as the declaration of the state of alarm in Spain. At the same time, the reorganization of the pediatric medical-surgical activities and infrastructures was carried out, with the consequent suspension of the non-urgent surgical activity of Pediatric Urology. We analyzed the impact of the COVID-19 pandemic on surgical activity in a Pediatric Urology division, as well as surgical complications according to the Clavien-Dindo classification. Materials and methods: A systematic review of epidemiological, clinical and surgical data was carried out, including complications and readmissions of all patients operated on in the division of Pediatric Urology within the duration of the state of alarm. Five time periods have been created according to the de-escalation phases. Results: Forty-nine surgical procedures were carried out on 45 patients (8 prior to the implementation of the de-escalation phases). High priority pathologies were the most frequent in the first phases, being the ureteropelvic junction (UPJ) obstruction the most prevalent. Four complications were recorded (8.8%), none of them were respiratory. Conclusions: The EAU recommendations for the resumption of surgical activity have allowed a correct, safe and gradual transition to the routine surgical activity in Pediatric Urology. The Clavien-Dindo classification is useful and valid for application in this division. No respiratory complications have been reported that could be attributable to the pandemic situation.


Are dental schools doing enough to prepare dental hygiene & therapy students for direct access?

-/- 2020; 7 (10): 36-7


Oral Health Sciences students views of the shift to remote teaching and assessment in response to COVID-19.

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Introduction An online survey investigated the views of students on the four-year Oral Health Sciences Honours degree course at Edinburgh University regarding the impact of COVID-19 on teaching and assessment. While delivery of remote teaching was generally viewed favourably, problem areas included clinic cancellations and clinical simulated case examinations. Oral Health Sciences graduates can practise as dental hygienist-therapists. Materials and methods An anonymous and voluntary online survey asked students to rate and comment on different formats of remote teaching and assessment. This material is supplemented by internal papers describing the planning and delivery of remote teaching and assessment. Results Nineteen of 29 students completed the survey (response rate: 66%). The interactive platform Collaborate was the most popular remote teaching format, although a number reported connectivity issues. Questionmark software, used to deliver a timed live examination, was rated highly. Cancellation of remaining clinical sessions was rated by Year 3 and 4 students as particularly problematic. Remote clinical simulated case examinations gave several students concerns. Other concerns were the impact on revision and adapting to different exam formats. Discussion The challenge was particularly complex as the curriculum involves a mixture of educational and clinical teaching and assessment, all requiring General Dental Council approval. Responses suggest remote teaching and assessment generally went smoothly. Results may help to inform future course development in this and similar courses in order to overcome or mitigate the negative impact of COVID-19. Conclusion The survey gave valuable and detailed feedback prior to the move to hybrid teaching.


An abundance of ambition.

-/- 2020; 7 (10): 14-5


Look after your hands.

-/- 2020; 7 (10): 6


CPD questions .

-/- 2020; 7 (10): 48


Ed s letter.

-/- 2020; 7 (10): 3


Manejo de pacientes con CPRCm tratados con dicloruro de radio-223 en el escenario del brote de COVID-19.

-/- 2020; 39 (6): 391-2


Cross-covariance based affinity for graphs.

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The accuracy of graph based learning techniques relies on the underlying topological structure and affinity between data points, which are assumed to lie on a smooth Riemannian manifold. However, the assumption of local linearity in a neighborhood does not always hold true. Hence, the Euclidean distance based affinity that determines the graph edges may fail to represent the true connectivity strength between data points. Moreover, the affinity between data points is influenced by the distribution of the data around them and must be considered in the affinity measure. In this paper, we propose two techniques, CCGAL and CCGAN that use cross-covariance based graph affinity (CCGA) to represent the relation between data points in a local region. CCGAL also explores the additional connectivity between data points which share a common local neighborhood. CCGAN considers the influence of respective neighborhoods of the two immediately connected data points, which further enhance the affinity measure. Experimental results of manifold learning on synthetic datasets show that CCGA is able to represent the affinity measure between data points more accurately. This results in better low dimensional representation. Manifold regularization experiments on standard image dataset further indicate that the proposed CCGA based affinity is able to accurately identify and include the influence of the data points and its common neighborhood that increase the classification accuracy. The proposed method outperforms the existing state-of-the-art manifold regularization methods by a significant margin.


The impact of a national COVID-19 lockdown on acute coronary syndrome hospitalisations in New Zealand (ANZACS-QI 55).

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Background: Countries with a high incidence of coronavirus 2019 (COVID-19) reported reduced hospitalisations for acute coronary syndromes (ACS) during the pandemic. This study describes the impact of a nationwide lockdown on ACS hospitalisations in New Zealand (NZ), a country with a low incidence of COVID-19. Methods: All patients admitted to a NZ Hospital with ACS who underwent coronary angiography in the All NZ ACS Quality Improvement registry during the lockdown (23 March ? 26 April 2020) were compared with equivalent weeks in 2015?2019. Ambulance attendances and regional community troponin-I testing were compared for lockdown and non-lockdown (1 July 2019 to 16 February 2020) periods. Findings: Hospitalisation for ACS was lower during the 5-week lockdown (105vs. 146 per-week, rate ratio 0?72 [95% CI 0?61?0?83], p=0.003). This was explained by fewer admissions for non-ST-segment elevation ACS (NSTE-ACS; p=0?002) but not ST-segment elevation myocardial infarction (STEMI; p=0?31). Patient characteristics and in-hospital mortality were similar. For STEMI, door-to-balloon times were similar (70vs. 72min, p=0?52). For NSTE-ACS, there was an increase in percutaneous revascularisation (59% vs. 49%, p<0?001) and reduction in surgical revascularisation (9% vs. 15%, p=0?005). There were fewer ambulance attendances for cardiac arrests (98vs. 110 per-week, p=0?04) but no difference for suspected ACS (408vs. 420 per-week, p=0?44). Community troponin testing was lower throughout the lockdown (182vs. 394 per-week, p<0?001). Interpretation: Despite the low incidence of COVID-19, there was a nationwide decrease in ACS hospitalisations during the lockdown. These findings have important implications for future pandemic planning. Funding: The ANZACS-QI registry receives funding from the New Zealand Ministry of Health.


SARS-CoV-2 is less likely to infect aquatic food animals: sequence and phylogeny analysis of ACE2 in mammals and fish.

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Telehealth: Samenwerken in de terminale zorg.

-/- 2020; 22 (5): 23-5


Covid-19, quelle information et quelle communication en priode d?incertitude?

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Associations between sociodemographic factors and physical activity and sedentary behaviors in adults with chronic diseases during COVID-19 pandemic.

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The pandemic of the new coronavirus (COVID-19) may be affecting the physical activity (PA) level in much of the population. This study aimed to investigate the prevalence of physical inactivity and sedentary behavior (SB) among adults with chronic diseases and their associations with sociodemographic factors during the COVID-19 pandemic. This cross-sectional study included 249 participants (age: 18?91 years; 61.4% female) with chronic conditions and attended the Family Health Strategy program in a small town in Brazil. Data were collected between 2020-07?13 and 2020-07-24 by face-to-face interviews. Self-reported PA, sitting time, chronic diseases, medication use, sociodemographic data, and self-isolation adherence were obtained by questionnaire. During this specific time point of the COVID-19 pandemic, 71.5% of participants did not meet the PA recommendations (?500 METs-min/week), and the prevalence of SB risk (?4?h sitting) was 62.7%. Adjusted logistic regression indicated that male participants (odds ratio [OR]: 1.89 [95% CI 1.02?3.53]), living alone (OR: 2.92 [95% CI 1.03?8.30]) or in a two-person household (OR: 2.32 [95% CI 1.16?4.63]), and those who reported sometimes performing self-isolation (OR: 3.07 [95% CI 1.47?6.40]) were more likely to meet the minimum PA recommendations. Current smokers had a lower odds (OR: 0.36 [95% CI 0.14?0.95]) of meeting the PA recommendations. Older participants (OR: 2.18 [95% CI 1.06?4.50]) and those who had multimorbidity (OR: 1.92 [95% CI 1.07?3.44]) were more likely to have a higher degree of SB. There is an urgent need to mitigate physical inactivity and SB, and public health interventions must take into account sociodemographic status.


Prise en charge par tlconsultation des patients diabtiques dans le contexte de la pandmie de la Covid-19: tude prospective observationnelle.

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The COVID-19 pandemic has compelled the French government to impose confinement measures to stem the spread of the coronavirus. These measures may have had a potential impact on the glycemic control of diabetic patients. Within this context, telemedicine appears to be a viable option for follow-up appointments of diabetic patients. To assess this theory, we simultaneously led a prospective observational study during the novel coronavirus pandemic at Strasbourg?s teaching hospital and at a private medical office to evaluate glycemic control in 491 diabetic patients either attending a telehealth appointment (n=338) or whom in-person consultation had been postponed by 6 months (n=153). Surveys were collected to assess both the patients? and the physicians? satisfaction. A decrease in average glycated hemoglobin (HbA1c) was observed among patients from the telehealth appointment group: ?HbA1c = -0.33% (n=175) as well as the other group: ?HbA1c = -0.13% (n=92) 3 months after the beginning of the study. Patients belonging to the telehealth appointment group at Strasbourg?s teaching hospital (n=97) experienced a decrease in their HbA1c average from 7.65 1.19% to 7.18 0.9%, while patients from the same group attending a private medical office (n=78) also experienced a decrease from 7.28 0.80% to 7.11 0.79%. Ninety-two percent of patients were satisfied with the telehealth appointment, think it could be a virtual alternative to in-person consultation and would recommend it to other diabetic patients. Even though seven out of eight diabetologists had never offered telehealth appointments to their patients prior to the COVID-19 pandemic, all of them hope to provide such services to their patients once the health crisis is over. The tendency towards a decrease in HbA1c levels within our cohort should be qualified due to missing data caused by the disruption in data collection during the COVID-19 pandemic. Evaluation and assessment of the cohort?s glycemic control 6 months after the beginning of the study could help confirm these results.



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Einleitung zum Forum: Die Corona-Pandemie ? Konflikt und Frieden in einer vernderten Welt.

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Corporatism, fractionalization and state interventionism: the development of communication studies in Brazil.

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This article summarizes the development of education and research in Communication Studies in Brazil. It is argued that different factors contributed to the development of the particular features that Brazilian Communication Studies present nowadays. They include: the late development of Brazilian universities, in comparison to the western societies, but also to other Latin American countries; the relatively early development of Communication programs, beginning from the late 1940s, following the example of the United States; state interventionism in the universities? curricula, and the influence exerted by other non-academic social actors, such as journalists? unions. As the result of the influence of these factors, Communication Studies organized according to two entirely different logics: undergraduate studies focus on specialized professional fields (such as Journalism, Advertising, Public Relations, Cinema) and adopt apractical approach with respect to them; otherwise, graduate studies employ amuch more general and academic approach focusing on Communication as awhole. The article also discusses the challenges faced by Communication Studies at present, resulting both from the changes in the media landscape and ahostile political scenario, associated with the rise of Jair Bolsonaro, an ultra-rightist politician who openly disdains science (and human sciences in particular).


Populismus und Bildung.

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Whither Critical Management and Organization Studies? For a Performative Critique of Capitalist Flows in the Wake of the COVID?19 Pandemic.

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Genome recoding strategies to improve cellular properties: mechanisms and advances.

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The genetic code, once believed to be universal and immutable, is now known to contain many variations and is not quite universal. The basis for genome recoding strategy is genetic code variation that can be harnessed to improve cellular properties. Thus, genome recoding is a promising strategy for the enhancement of genome flexibility, allowing for novel functions that are not commonly documented in the organism in its natural environment. Here, the basic concept of genetic code and associated mechanisms for the generation of genetic codon variants, including biased codon usage, codon reassignment, and ambiguous decoding, are extensively discussed. Knowledge of the concept of natural genetic code expansion is also detailed. The generation of recoded organisms and associated mechanisms with basic targeting components, including aminoacyl-tRNA synthetase?tRNA pairs, elongation factor EF-Tu and ribosomes, are highlighted for a comprehensive understanding of this concept. The research associated with the generation of diverse recoded organisms is also discussed. The success of genome recoding in diverse multicellular organisms offers a platform for expanding protein chemistry at the biochemical level with non-canonical amino acids, genetically isolating the synthetic organisms from the natural ones, and fighting viruses, including SARS-CoV2, through the creation of attenuated viruses. In conclusion, genome recoding can offer diverse applications for improving cellular properties in the genome-recoded organisms.


Introduction to the special issue on analytical and decision-making technique innovation in financial market.

-/- 2020; 6 (1):


? Time course of lung changes on thoracic ultrasound of mildCOVID-19 patients?.

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Adamantanos para la prevencin del COVID-19.

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Detection of respiratory viruses in patients with suspected SARS-CoV-2 infection?.

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Impfdosen-Knappheit und Corona: ein neuer Stresstest?

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Assessment of trends and clinical presentation in the emergency department of patients with renal colic during the COVID-19 pandemic era?.

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Introduction: We hypothesized that the recent COVID-19 pandemic may lead to a delay in renal colic patients presenting to the Emergency Department due to the fear of getting infected. This delay may lead to a more severe clinical condition at presentation with possible complications for the patients. Material and methods: Retrospective review of data collected from three institutions from Spain and Italy. Patients who presented to Emergency Department with unilateral or bilateral renal colic caused by imaging confirmed urolithiasis during the 45 days before and after each national lockdown were included. Data collected included patients? demographics, biochemical urine and blood tests, radiological tests, signs, symptoms and the therapeutic management. Analysis was performed between two groups, Group A: patients presenting prior to the national lockdown date; and Group B: patients presenting after the national lockdown date. Results: A total of 397 patients presented to Emergency Department with radiology confirmed urolithiasis and were included in the study. The number of patients presenting to Emergency Department with renal/ureteric colic was 285 (71.8%) patients in Group A and 112 (28.2%) patients in Group B (p<0.001). The number of patients reporting a delay in presentation was 135 (47.4%) in Group A and 63 (56.3%) in Group B (p=0.11). At presentation, there were no statistical differences between Group A and Group B regarding the serum creatinine level, C reactive protein, white blood cell count, fever, oliguria, flank pain and hydronephrosis. In addition, no significant differences were observed with the length of stay, Urology department admission requirement and type of therapy. Conclusion: Data from our study showed a significant reduction in presentations to Emergency Department for renal colic after the lockdown in Spain and Italy. However, we did not find any significant difference with the length of stay, Urology department admission requirement and type of therapy.


Comparison of the demographic characteristics and comorbidities of patients with COVID-19 who died in Spanish hospitals based on whether they were or were not admitted to an intensive care unit?.

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Objective: To describe and compare the demographic characteristics and comorbidities of patients with COVID-19 who died in Spanish hospitals during the 2020 pandemic based on whether they were or were not admitted to an intensive care unit (ICU) prior to death. Methods: We performed a secondary analysis of COVID-19 patients who died during hospitalization included by 62 Spanish emergency departments in the SIESTA cohort. We collected the demographic characteristics and comorbidities, determined both individually and estimated globally by the Charlson index (ChI). Independent factors related to ICU admission were identified and different analyses of sensitivity were performed to contrast the consistency of the findings of the principal analysis. Results: We included the 338 patients from the SIESTA cohort that died during hospitalization. Of these, 77 (22.8%) were admitted to an ICU before dying. After multivariate adjustment, 3 out of the 20 basal characteristics analyzed in the present study were independently associated with ICU admission: dementia (no patients with dementia who died were admitted to the ICU: OR = 0, 95%CI = not calculable), active cancer (OR = 0.07; 95%CI = 0.02-0.21) and age (< 70 years: OR = 1, reference; 70-74 years: OR = 0.21; 95%CI = 0.08-0.54; 75-79 years: OR = 0.21; 95%CI = 0.08-0.54; ? 80 years: OR = 0.02; 95%CI = 0.01-0.05). The probability of ICU admission significantly increased in parallel to the ChI, even after adjustment for age (ChI 0 points: OR = 0, reference; ChI 1 point: OR = 0.36; 95%CI = 0.16-0.83; ChI 2 points: OR = 0.36; 95%CI = 0.16-0.83; ChI >2 points: OR = 0.09; 95%CI = 0.04-0.23). The sensitivity analyses showed no gross differences compared to the principal analysis. Conclusions: The profile of COVID-19 patients who died without ICU admission is similar to that observed in the usual medical practice before the pandemic. The basal characteristics limiting their admission were age and global burden due to comorbidity, especially dementia and active cancer.


Urological surgery during SARS-CoV-2 pandemic. Descriptive analysis of the experience in a Urology Department across the pandemic phases?.

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Introduction: The SARS-CoV-2 pandemic has changed the urological practice around the world. Our objective is to describe the outcomes presented by patients undergoing surgery in the urology department of a tertiary hospital, across the pandemic phases. Methods: Observational, cohort study including all patients undergoing surgery from March 1 to May 14. According to the hospital organization, we identified three periods: there were no changes during the first two weeks (1st. period), the following seven weeks, when only urgent interventions were carried out after performance of nasopharyngeal swab test (2nd. period), and finally, elective surgery was resumed on May 4, after the implementation of a multidisciplinary screening protocol (3rd. period). Demographic, baseline, surgical and perioperative variables, as well as postoperative outcomes, were obtained in a retrospective (periods 1 and 2) and prospective (period 3) manner. Telephone follow-up was initiated at least 3 weeks after hospital discharge. Results: 103 urological surgeries were performed, and 11 patients were diagnosed with COVID-19, 8 of them within the 1st. period. The diagnosis was already known in 1 patient, while the other 10 developed the disease in an average of 25 days after the intervention and 16,6 days after discharge. Of seven transplant patients, four got the infection. Three deaths were recorded due to the disease: a 69-year-old woman transplanted and two men over 80 with comorbidities and high anesthetic risk who underwent drainage of retroperitoneal abscess and retrograde intrarenal surgery, respectively. Conclusions: SARS-CoV-2 infection mainly affected renal transplant recipients or elderly patients with high anesthetic risk, during the first 2 weeks of the pandemic. After implementing preoperative PCR tests and a comprehensive screening protocol, cases were substantially reduced, and safe surgical procedures were achieved.


New approaches to housing complexity: designing dwellings in the age of cognitive economy.

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Space is produced by a society in accordance with its habits, and habits, mostly in the Western society, have been heavily influenced by forms of production. Indeed, it is widely acknowledged that the Industrial Revolution definitely changed the space of modern landscapes, cities and dwellings life at all scales, and the way in which we perceive them. Cognitive capitalism is no exception. Since it fully established itself as one of the prevailing economic forces in the 21st century and in the Western world, it produced deep changes in the way in which people work, connect, and live. Starting from the assumption that changes in means of production generate new social relationships, this paper investigates how these changes might result in new ways of building architectural space. Without indulging in a deterministic attitude, it focuses on housing as one of the fundamental artefacts where a society expresses its approach to space. The house is a basic element of complex urban systems and is, therefore, the one calling for a more radical conceptual rethinking, marking an effective distance with the forms inherited from the previous centuries. Finally, the paper aims at understanding the repercussions of the digital paradigm on the space of dwelling, reasoning on some crucial questions to understand how housing might evolve, unfolding through its spatial configuration the new ways of life of the digital society.


In silico molecular docking and molecular dynamic simulation of potential inhibitors of 3C-like main proteinase (3CLpro) from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) using selected african medicinal plants.

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The Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) is an infectious virus that causes mild to severe life-threatening upper respiratory tract infection. The virus emerged in Wuhan, China in 2019, and later spread across the globe. Its genome has been completely sequenced and based on the genomic information, the virus possessed 3C-Like Main Protease (3CLpro), an essential multifunctional enzyme that plays a vital role in the replication and transcription of the virus by cleaving polyprotein at eleven various sites to produce different non-structural proteins. This makes the protein an important target for drug design and discovery. Herein, we analyzed the interaction between the 3CLpro and potential inhibitory compounds identified from the extracts of Zingiber offinale and Anacardium occidentale using in silico docking and Molecular Dynamics (MD) Simulation. The crystal structure of SARS-CoV-2 main protease in complex with 02J (5-Methylisoxazole-3-carboxylic acid) and PEJ (composite ligand) (PDB Code: 6LU7, 2.16) retrieved from Protein Data Bank (PDB) and subject to structure optimization and energy minimization. A total of twenty-nine compounds were obtained from the extracts of Z. offinale and the leaves of A. occidentale. These compounds were screened for physicochemical (Lipinski rule of five, Veber rule, and Egan filter), Pan-Assay Interference Structure, and pharmacokinetic properties to determine the Pharmaceutical Active Ingredients. Of the 29 compounds, only nineteen (19) possessed drug-likeness properties with efficient oral bioavailability and less toxicity. These compounds subjected to molecular docking analysis to determine their binding energies with the 3CLpro. The result of the analysis indicated that the free binding energies of the compounds ranged between ??5.08 and ??10.24kcal/mol, better than the binding energies of 02j (??4.10kcal/mol) and PJE (??5.07kcal/mol). Six compounds (CID_99615?=???10.24kcal/mol, CID_3981360?=?9.75kcal/mol, CID_9910474?=???9.14kcal/mol, CID_11697907?=???9.10kcal/mol, CID_10503282?=???9.09kcal/mol and CID_620012?=???8.53kcal/mol) with good binding energies further selected and subjected to MD Simulation to determine the stability of the protein?ligand complex. The results of the analysis indicated that all the ligands form stable complexes with the protein, although, CID_9910474 and CID_10503282 had a better stability when compared to other selected phytochemicals (CID_99615, CID_3981360, CID_620012, and CID_11697907).


Die Pandemie offenbart die Defizite des transnationalen Menschenrechtsschutzes: Ein Pldoyer fr eine Konfliktperspektive auf globale Lieferketten.

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The corona pandemic has led to amassive disruption of global supply chains and has thus existentially affected the export economies of many producing countries. This is particularly dramatic for workers at the beginning of the value chain. The violations of internationally recognized social and economic rights in global supply chains are more massive today than before the crisis and reveal afar-reaching potential for new conflicts. The article illustrates this situation in the case of Brazil and India and, on this basis, raises the issue of global supply chains as atopic for peace and conflict research. Supply chains are spaces of political conflict about material and ideological conditions of production, which are shaped by avariety of institutional contexts and actors. One of the most controversial issues is the lack of labour and human rights protection. The dominant way to address this lack is through institutions and practices of transnational private governance?standards, certification, monitoring and audits. In the pandemic, these already patchy approaches reveal that, especially in times of crisis, they are unsuitable for securing basic labour and human rights and for pacifying existing conflicts. The article concludes with an emphasis of the linkages between global supply chains and local conflicts and argues for an extended research agenda on ?supply chains and conflict?.


Covid-19: equal response and unequal interests.

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The greatest risks of Covid-19 are not arising from its direct effects on morbidity and mortality but from exaggerated aspirations to control such effects politically. A swift transformation from an epidemic to an endemic state of affairs may in case of a disease with comparatively low and unequally distributed mortality like covid-19 be an option, too. This needs to be laid out but it is not the task of science to plead for this or any other option.


Incidence of surgical abdominal emergencies during SARS-CoV-2 pandemic?.

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A Peer-Reviewed Scholarly Article.

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A New Compartmental Epidemiological Model for COVID-19 with a Case Study of Portugal.

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?New compartmental mathematical model for the spread of the COVID-19 disease.?COVID-19 pandemic in Portugal till the end of the three states of emergency.?Simultaneous description of active infected and hospitalized individuals.?Reproduction number in agreement with the one of Portuguese Health authorities.?The possibility of a second wave of COVID-19 in Portugal is not ruled out.


Freiheitsentziehende Manahmen in der Geriatrie.

-/- 2020; 15 (4): 6-8


Aktuelles zum Impfen im Alter - STIKO Empfehlungen 2020/2021.

-/- 2020; 15 (4): 9-11


The EU Rule of Law Initiative Towards the Western Balkans.

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The EU adopted a new enlargement strategy for the Western Balkans countries in 2018, provided a time frame for Serbia and Montenegro potentially to join the Union by 2025, and outlined the next steps for accession for Albania, Bosnia and Herzegovina, Kosovo, and North Macedonia. In March 2020, the EU gave the green light to the opening of accession talks with North Macedonia and Albania, and also introduced a new reformed ?accession talks? framework. The strengthening of the rule of law, fighting corruption and organised crime are the cornerstones of the EU-Western Balkans strategy of 2018 and the new accession talks framework of 2020. This article examines the latest enlargement policy developments in 2018?2020 by conceptualising how the EU promotes the rule of law in the Western Balkans thorough its new enlargement policy package. Furthermore, the article offers an in-depth analysis of the case of Albania, where the EU has experimented with some of its latest enlargement-policy ideas in regard to the rule of law. The article also offers some proposals and insights on how the EU rule of law initiative of 2018 can be improved, in order to become more transformative in strengthening the rule of law in countries of the Western Balkans.


Voting Originated Social Dynamics: Quartile Analysis of Stochastic Environment Peculiarities.

-/- 2020; 81 (10): 1865-83

The model of voting originated social dynamics in a stochastic environment (the ViSE model) is considered. Within this model, the influence of the heaviness of distribution tails on the effectiveness of egoistic and altruistic strategies in terms of maximizing two criteria, the average capital increment and the number of non-bankrupt participants, is investigated. Homogeneous societies and four types of distributions used to generate proposals (Gaussian, logistic, Student?s with 3 degrees of freedom, and symmetrized Pareto distributions) are studied. To assess the effect of tail heaviness, all distributions are unified by quartile using scatter. Such an approach can be used to compare the heavy-tailed distributions that are commensurable by density with other distributions under consideration on an interval containing 90% of observations.


Leukocyte count in COVID-19: an important consideration.

-/- 2020; 14 (1):


An assessment of import tariff costs for Italian exporting firms.

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Since production and trade are increasingly organized within global value chains (GVCs), assessing who effectively pays the cost of protection is not straightforward and since productive processes are internationally fragmented, quantifying the effects of trade policy requires an enhanced analytical framework that takes international input?output linkages into account to assess the implications trade costs have on competitiveness at national and sector levels. This paper defines a new synthetic measure of trade protection based on the value added in trade, capturing the effects that the tariff structure has on exporting firms that rely on imported intermediate inputs. The index, defined in a general equilibrium framework, provides a theoretically sound protection measurement in the context of GVCs. We assess trade protection by computing protection indexes at the bilateral level on both gross imports and imports to exports using the Global Trade Analysis Project computable general equilibrium model. These indexes are used to investigate the relationship between the European Union tariffs and integration of the Italian GVCs. In the case of Italy, imports to exports are overall less protected than gross imports with significant differences at the sector level. Despite the low levels of nominal protection, industrial sectors play a central role in explaining our results. EU tariffs mostly affect Italian exporting firms in the case of chemical products, wearing apparel and leather products.Electronic supplementary material: The online version of this article (10.1007/s40888-020-00202-8) contains supplementary material, which is available to authorized users.


Alles online - alles gut?

-/- 2020; 68 (11): 844-5


"Wir halten eine andere Vorgehensweise fr sinnvoll": rzteschaft prsentiert Positionspapier zur COVID-19-Pandemie.

-/- 2020; 68 (11): 836-7


"Ambulante Versorgung bildet den Schutzwall": KBV-Webkonferenz zeigt starke Gesundheitssysteme 2020.

-/- 2020; 68 (11): 838-9


The COVID-19 Pandemic and the Ongoing Genocide of Black and Indigenous Peoples in Brazil.

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Cardinal Czerny has compared COVID-19 with a magnifying glass and an X-ray; this article reflects on the tragedy of the Brazilian experience with the COVID-19 pandemic and the deeper wounds it reveals and magnifies. Drawing from journalistic reports, firsthand accounts, statistics, and existing academic literature on race and racism in Brazil, this article interrogates Brazilian racialized society and how the racial divide and economic disparities have been exacerbated through the devastating impact of the pandemic upon a large parcel of the Brazilian people, focusing particularly on how the pandemic magnifies and intensifies the genocide of black and indigenous Brazilians. The article also underscores how Bolsonaro?s strong man politics aggravates the situation, and scrutinizes the ambiguous role of religion in the construction and exacerbation of structural racism as well as in offering creative responses to the current situation.


En poca de pandemia, no todo es covid-19.

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One in Three Luxembourg Residents Report their Mental Health Declined during the COVID-19 Crisis.

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COVID-19 has had unprecedented effects on people around the world, causing even the best performing communities to live in uncertainty for the future. How are people coping? We ? the general public, the academic community, and policy makers ? need answers. To that end we analyse novel data for Luxembourg, finding one third of residents report their mental health declined during lockdown and young adults (ages 18?44) fared the worst. The most important contributors observed are physical health, income, and employment characteristics, such as working from home, which people seemed to enjoy. To limit collateral damage on mental health, various tools are available, which we briefly discuss.


Japan?s strategy amid US?China confrontation.

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Japan?s strategy amid US?China confrontation has focused on securing national defense and economic prosperity by maintaining Japan?s alliance with the United States and promoting Asia?s socioeconomic integration. Japan is working toward an institutional order based on universal values. It realizes that such a long-term goal requires coexistence, including with countries in the midst of integrating into the political and economic world order, and prioritizes stability. This approach explains the historical development of Japan?China relations since the 1970s. During this period, Japan has expected to maneuver China into integration with global politics through economic statecraft while maintaining its alliance with the US. During the current US?China confrontation, Japan faces the challenge of maintaining this complex strategic position in the US?China?Japan triangle. Its reaction to this new reality is to enhance its alliance with the US (including cooperation for economic security) and strengthen international partnership to promote its preferred mode of institutional order, while maintaining diplomacy with China.


Integrating competency-based education with a case-based or problem-based learning approach in online health sciences.

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In the current competitive and globalized economy, employers and professional organizations call for higher education institutions to deliver graduates with relevant competencies and skills. In response, a growing number of higher educational institutions is introducing competency-based education. This is particularly true for health science programs, which have a tradition of applying a case-based or problem-based learning approach. The effort to merge a problem- or case-based online learning approach with competency-based education offers various opportunities, while facing numerous challenges. To support these efforts, this paper aims at identifying suitable practices, as well as challenges for online course design and online learning activities for higher education health science programs, when integrating competency-based education with an online problem-based and/or case-based learning approach. It found various opportunities for online learning activities that support competency-based education, problem-based learning and case-based learning, whereas challenges relate to logistics, administration, and the affordances of an LMS.Electronic supplementary material: The online version of this article (10.1007/s12564-020-09658-6) contains supplementary material, which is available to authorized users.


Experimental investigation of a decentralized heat recovery ventilation system.

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Indoor air quality is an important issue for improving and maintaining the indoor environment because it is directly related to people s health and work performance. These days, in many settlements, the applicability of natural ventilation is limited in the face of the decreasing infiltration loads, increased atmospheric pollution, and the climatic conditions. Therefore, the use of mechanical systems that are designed to ensure proper ventilation is becoming widespread. This paper presents full-scale experimental research of a wall-integrated decentralized ventilation system with heat recovery in the laboratory conditions. The heat recovery unit includes a ceramic block for sensible thermal energy storage. Parametric experimental studies were carried out to obtain the temperature distributions and the thermal capacity of the ceramic block during the supply and exhaust modes of working. In order to simulate the winter and summer conditions, two large scale temperature-controlled rooms are built up. The duration of the ventilation period is varied to be 1, 2, 5, 7.5 and 10-min. Experimental measurements indicate that 2min of operation time shows the best thermal performance in terms of maintaining a comfortable indoor temperature with the least energy consumption. And some shortcomings were observed about the fan and thermal storage limitations.


Afterword: new horizons in materiality and literature.

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This article is an afterword (in every sense of that word) on a special collection about ?materiality and literature.? It follows up on a promise that Thomas Bremer makes at the end of the Introduction to the special issue, where he acknowledges that there are ?new horizons? waiting to be explored in theorizing about the topic. Most prominently visible on these new horizons, but not mentioned in the articles themselves, is what has been called ?the new materialism.? This article explores very briefly the contributions of this burgeoning field, touching on matters relating with the current Covid-19 pandemic, climate change, and the state of the humanities itself.


Dermapraxis Berlin schlgt der Pandemie ein Schnippchen: Bewhrtes Fortbildungsformat - und sogar in Prsenz.

-/- 2020; 68 (11): 854-5


Keine Wirtschaftlichkeitsprfungen fr 2019: In Rheinland-Pfalz wurde das Ausgabenvolumen eingehalten.

-/- 2020; 68 (11): 850-1


Nutzen und Risiken sorgsam abwgen.

-/- 2020; 68 (11): 856-67


Pandemics and Network Scholarship.

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Influence of cardiovascular disease and cardiovascular risk factors in Covid-19 patients. Data from a large prospective Spanish cohort.

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Introduction and objectives: Coronavirus disease 2019 (COVID-19) has become a pandemic infection. Retrospective data showed worse outcomes in patients with cardiovascular disease (CVD) and cardiovascular (CV) risk factors. We sought to evaluate the link between CVD and CV risk factors with in-hospital outcomes in COVID-19.Methods: We designed a prospective registry that included consecutive COVID-19 patients admitted at our institution. The inclusion period was from 27 February to 7 April 2020. Clinical outcomes were monitored up to 2 May 2020.Results: A total of 876?patients were included. Mean age was 62??18 years old; 47% were?>?65 years of age. A total of 69% of patients had at least one CV risk factor; 15% of the patients had previous history of CVD. Patients with previous CVD were significantly older (77??11 vs 60??18 years old; P??65 years old (OR, 15; 95%CI, 5-43), chronic congestive heart failure (OR,?3.27; 95%CI, 1.38-7.72) and chronic kidney disease (OR, 8.55; 95%CI, 1.47-5.46) as independent predictors of death.Conclusions: In patients admitted for COVID-19, CVD or CV risk factors are associated with an increased risk of death during hospitalization. We found that older age, history of congestive heart failure and chronic kidney disease are independent predictors of death in COVID-19.


Das Potenzial der Bewegungsfrderung: Ganztagsschule und Sportverein ? einPraxisbeispiel.

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Das Virus, der Sport und die Herausforderungen: Fragen an die Wissenschaft.

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Attention-based VGG-16 model for COVID-19 chest X-ray image classification.

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Computer-aided diagnosis (CAD) methods such as Chest X-rays (CXR)-based method is one of the cheapest alternative options to diagnose the early stage of COVID-19 disease compared to other alternatives such as Polymerase Chain Reaction (PCR), Computed Tomography (CT) scan, and so on. To this end, there have been few works proposed to diagnose COVID-19 by using CXR-based methods. However, they have limited performance as they ignore the spatial relationships between the region of interests (ROIs) in CXR images, which could identify the likely regions of COVID-19?s effect in the human lungs. In this paper, we propose a novel attention-based deep learning model using the attention module with VGG-16. By using the attention module, we capture the spatial relationship between the ROIs in CXR images. In the meantime, by using an appropriate convolution layer (4th pooling layer) of the VGG-16 model in addition to the attention module, we design a novel deep learning model to perform fine-tuning in the classification process. To evaluate the performance of our method, we conduct extensive experiments by using three COVID-19 CXR image datasets. The experiment and analysis demonstrate the stable and promising performance of our proposed method compared to the state-of-the-art methods. The promising classification performance of our proposed method indicates that it is suitable for CXR image classification in COVID-19 diagnosis.


Social Media and Coronavirus: Paranoid-Schizoid Technology and Pandemic?

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This article draws on the psychoanalyst Melanie Klein?s ?paranoid-schizoid position? to discuss some exemplary social media posts about the coronavirus. I argue that posts often express experiences, thoughts, and fantasies in a schematic manner. They reproduce a paranoid-schizoid logic by which particular views on the current crisis are articulated and different ones are negated. The Kleinian framework is supplemented with Lacan?s notion of the Discourse of the Hysteric. I argue that the examples discussed in this article are instances of hysteric modes of relating to an Other (e.g. the expert) that is allegedly withholding important information from the subject. Splitting is amplified by the technological functioning of social media themselves which split users along a paranoid-schizoid dynamic for purposes of surveillance, advertising and profit maximization. I conclude by outlining steps towards the Kleinian ?depressive position? both in relation to how we engage with COVID-19 and social media. The depressive position acknowledges both good and bad aspects of a given situation. I further show how it can be supplemented via the Lacanian Discourse of the Analyst which includes a commitment to the limits of knowledge, certainty, and prediction.


COVID-19 pandemic: An analysis of the healthcare, social and economic challenges in Bangladesh.

-/- 2020; 8 (): 100135

Bangladesh is one of the worst hit countries in South Asia for COVID-19 outbreak. The objective of this article is to analyse healthcare, social and economic challenges faced by the country. Quantitative data and qualitative information from different sources have been used. Our analysis indicates that limited well-equipped hospitals, inadequate testing facilities, lack of awareness, improper knowledge, attitude to and practice of rules, poverty and precarious employment are the factors dominant in spreading COVID-19. Strict enforcement measures and ensuring people s adherence to rules may help reduce spread of infections. Adequate healthcare services are essential for establishing proper medical care.


Sensemaking in the Time of COVID?19.

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COVID-19 pandemic crisis?a complete outline of SARS-CoV-2.

-/- 2020; 6 (1):

Background: Coronavirus (SARS-CoV-2), the cause of COVID-19, a fatal disease emerged from Wuhan, a large city in the Chinese province of Hubei in December 2019. Main body of abstract: The World Health Organization declared COVID-19 as a pandemic due to its spread to other countries inside and outside Asia. Initial confirmation of the pandemic shows patient exposure to the Huanan seafood market. Bats might be a significant host for the spread of coronaviruses via an unknown intermediate host. The human-to-human transfer has become a significant concern due to one of the significant reasons that is asymptomatic carriers or silent spreaders. No data is obtained regarding prophylactic treatment for COVID-19, although many clinical trials are underway. Conclusion: The most effective weapon is prevention and precaution to avoid the spread of the pandemic. In this current review, we outline pathogenesis, diagnosis, treatment, ongoing clinical trials, prevention, and precautions. We have also highlighted the impact of pandemic worldwide and challenges that can help to overcome the fatal disease in the future.


Special Issue: Statistical mathematics for ecological and environmental data.

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How the pandemic taught us to turn smart beta into real alpha.

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The ongoing COVID-19 pandemic has strongly reminded equity investors that rare but extreme events occur from time to time. At the individual firm level, such events also impact the likelihood of bankruptcy, a feature that is not well represented in the traditional Capital Asset Pricing Model. This paper presents a functional form for equity asset pricing that is realistic, and reconciles the observed high equity risk premium with the observed lower than expected slope of the Security Market Line. Most importantly, we will demonstrate how including the potential for such large events changes traditional views of equity returns and the known factors that contribute to those returns. On the basis of empirical examination of a dataset stretching over 30 years without survivorship bias, we conclude that when the probabilities of rare extreme events are considered, strategies that focus on ?alpha? (risk adjusted return) as defined in Jensen (J Finance 23(2):389?416, 1967) are structurally superior to ?smart beta? strategies that seek to outperform a market index benchmark.


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